| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4007647 | Binding | Inhibition of C-terminal His-tagged Syk catalytic domain (356 to 635 residues) (unknown origin) using biotin-TYR1 as substrate after 60 mins by TR-FRET assay | Homo sapiens | 19 | ALA4007384 | single protein format | Scientific Literature | |
| 2. | ALA4007648 | Binding | Inhibition of Syk in human Ramos B cells assessed as decrease in intracellular calcium flux measured for 3.5 mins by calcium-5 dye based FLIPR assay | Homo sapiens | 17 | ALA4007384 | cell-based format | Scientific Literature | |
| 3. | ALA4007649 | ADME | Unbound clearance in rat microsomes | Rattus norvegicus | 14 | ALA4007384 | assay format | Scientific Literature | |
| 4. | ALA4007650 | ADME | Unbound clearance in human microsomes | Homo sapiens | 9 | ALA4007384 | assay format | Scientific Literature | |
| 5. | ALA4007651 | Physicochemical | Solubility in pH 5 FeSSIF at 0.2 mg sonicated for 10 mins followed by incubation for 2 days by HPLC analysis | 7 | ALA4007384 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4007653 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 10 uM measured immediately relative to control | Homo sapiens | 3 | ALA4007384 | assay format | Scientific Literature | |
| 7. | ALA4007654 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 50 uM measured immediately relative to control | Homo sapiens | 3 | ALA4007384 | assay format | Scientific Literature | |
| 8. | ALA4007655 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 10 uM measured after 30 mins relative to control | Homo sapiens | 3 | ALA4007384 | assay format | Scientific Literature | |
| 9. | ALA4007656 | ADME | Inhibition of CYP3A4 in human liver microsomes assessed as residual activity at 50 uM measured after 30 mins relative to control | Homo sapiens | 3 | ALA4007384 | assay format | Scientific Literature | |
| 10. | ALA4007680 | Binding | Inhibition of ABL (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 11. | ALA4007681 | Binding | Inhibition of ACVR1 (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 12. | ALA4007682 | Binding | Inhibition of AKT (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 1 | ALA4007384 | single protein format | Scientific Literature | |
| 13. | ALA4007683 | Binding | Inhibition of ALK (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 14. | ALA4007684 | Binding | Inhibition of AMPK (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | assay format | Scientific Literature | |
| 15. | ALA4007685 | Binding | Inhibition of AURKA (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 16. | ALA4007686 | Binding | Inhibition of AURKB (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 17. | ALA4007687 | Binding | Inhibition of BRAF (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 2 | ALA4007384 | single protein format | Scientific Literature | |
| 18. | ALA4007688 | Binding | Inhibition of BTK (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 19. | ALA4007689 | Binding | Inhibition of human CAMK1D (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature | |
| 20. | ALA4007690 | Binding | Inhibition of human CAMK2A (unknown origin) after 60 mins by TR-FRET assay | Homo sapiens | 5 | ALA4007384 | single protein format | Scientific Literature |
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