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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4049137 | B | Inhibition of human PDE2A1 using 3',5'-[3H]cGMP as substrate after 30 mins by scintillation proximity assay | Homo sapiens | 41 | ALA4043302 | single protein format | Scientific Literature | |
2. | ALA4049138 | A | Intrinsic clearance in human hepatocytes assessed per million cells at 1 uM after 0.5 to 4 hrs by HPLC-HRMS method | Homo sapiens | 25 | ALA4043302 | cell-based format | Scientific Literature | |
3. | ALA4049139 | A | Apparent permeability across RRCK cells after 1.5 hrs | Canis lupus familiaris | 37 | ALA4043302 | cell-based format | Scientific Literature | |
4. | ALA4049162 | A | Drug metabolism in human liver microsomes assessed as 5-(5-((2-Hydroxycyclopentyl)methyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazin-3-yl)-7-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one diastereomer 1 formation at 20 uM after 1.5 hrs by UHPLC-UV-HRMS method | Homo sapiens | 1 | ALA4043302 | assay format | Scientific Literature | |
5. | ALA4049177 | A | Drug metabolism in human liver microsomes assessed as 5-(5-((2-Hydroxycyclopentyl)methyl)-4,5,6,7-tetrahydropyrazolo-[1,5-a]pyrazin-3-yl)-7-methylimidazo[5,1-f][1,2,4]triazin-4(3H)-one diastereomer 2 formation at 20 uM after 1.5 hrs by UHPLC-UV-HRMS method | Homo sapiens | 1 | ALA4043302 | assay format | Scientific Literature |