#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4029856	B	Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation at 1 uM using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min relative to control	Homo sapiens	18	ALA4028818	cell-based format	Scientific Literature
2.	ALA4029857	B	Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation at 10 uM using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min relative to control	Homo sapiens	18	ALA4028818	cell-based format	Scientific Literature
3.	ALA4029858	B	Inhibition of recombinant human mPGES-1 expressed in CHO cells assessed as reduction in PGE2 formation using PGH2 a substrate preincubated for 10 mins followed by substrate addition measured after 1 min	Homo sapiens	42	ALA4028818	cell-based format	Scientific Literature
4.	ALA4029859	B	Inhibition of mPGES-1 in human A549 cells assessed as decrease in IL1beta induced PGE2 release preincubated for 30 mins followed by IL-1beta addition after 16 to 20 hrs by HTRF method	Homo sapiens	18	ALA4028818	cell-based format	Scientific Literature
5.	ALA4029860	A	Inhibition of COX1 in human U937 cells assessed as decrease in PGE2 release using arachidonic acid as substrate preincubated for 15 mins followed by arachidonic acid addition measured after 5 mins	Homo sapiens	3	ALA4028818	cell-based format	Scientific Literature
6.	ALA4029861	A	Inhibition of recombinant human N-terminal His-tagged COX2 expressed in baculovirus infected Sf21 insect cells assessed as decrease in PGE2 release using arachidonic acid as substrate preincubated for 15 mins followed by arachidonic acid addition measured after 5 mins	Homo sapiens	3	ALA4028818	cell-based format	Scientific Literature
7.	ALA4029862	A	Metabolic stability in human liver microsomes assessed as parent compound remaining at 1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis	Homo sapiens	4	ALA4028818	assay format	Scientific Literature
8.	ALA4029863	A	Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis	Rattus norvegicus	4	ALA4028818	assay format	Scientific Literature
9.	ALA4029864	A	Metabolic stability in Guinea pig liver microsomes assessed as parent compound remaining at 1 uM after 60 mins in presence of NADPH by LC/MS/MS analysis	Cavia porcellus	4	ALA4028818	assay format	Scientific Literature
10.	ALA4029865	A	Inhibition of CYP1A2 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control	Homo sapiens	4	ALA4028818	assay format	Scientific Literature
11.	ALA4029866	A	Inhibition of CYP2D6 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control	Homo sapiens	4	ALA4028818	assay format	Scientific Literature
12.	ALA4029867	A	Inhibition of CYP3A4 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control	Homo sapiens	4	ALA4028818	assay format	Scientific Literature
13.	ALA4029868	A	Inhibition of CYP2C9 in human liver microsomes at 10 uM measured after 20 mins in presence of NADPH by LC/MS/MS analysis relative to control	Homo sapiens	4	ALA4028818	assay format	Scientific Literature
14.	ALA4029869	A	Protein binding in human plasma at 10 uM after 5 to 10 mins by LC-MS/SM analsysis	Homo sapiens	4	ALA4028818	cell-free format	Scientific Literature
15.	ALA4029870	A	Protein binding in Guinea pig plasma at 10 uM after 5 to 10 mins by LC-MS/SM analysis	Cavia porcellus	4	ALA4028818	cell-free format	Scientific Literature
16.	ALA4029871	A	Half life in Sprague-Dawley rat at 5 mg/kg, iv administered as single bolus dose	Rattus norvegicus	2	ALA4028818	organism-based format	Scientific Literature
17.	ALA4029872	A	Clearance in Sprague-Dawley rat at 5 mg/kg, iv administered as single bolus dose	Rattus norvegicus	2	ALA4028818	organism-based format	Scientific Literature
18.	ALA4029873	A	Apparent volume of distribution in Sprague-Dawley rat at 5 mg/kg, iv administered as single bolus dose	Rattus norvegicus	2	ALA4028818	organism-based format	Scientific Literature
19.	ALA4029874	A	Cmax in Sprague-Dawley rat at 10 mg/kg, po	Rattus norvegicus	2	ALA4028818	organism-based format	Scientific Literature
20.	ALA4029875	A	AUC (0 to 24 hrs) in Sprague-Dawley rat at 10 mg/kg, po	Rattus norvegicus	2	ALA4028818	organism-based format	Scientific Literature