# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4362357 | ADME | Cytotoxicity against human SH-SY5Y cells assessed as cell viability at 1 uM measured after 48 hrs by MTT assay relative to control | Homo sapiens | 18 | ALA4359872 | cell-based format | Scientific Literature | |
2. | ALA4362358 | ADME | Cytotoxicity against human SH-SY5Y cells measured after 48 hrs by MTT assay | Homo sapiens | 18 | ALA4359872 | cell-based format | Scientific Literature | |
3. | ALA4362359 | Binding | Inhibition of recombinant mouse wild-type NAMPT expressed in bacterial expression system using PRPP as substrate in presence of mouse NMNAT-3 measured for 1 hr by fluorescence assay | Mus musculus | 18 | ALA4359872 | assay format | Scientific Literature | |
4. | ALA4008461 | Binding | Inhibition of recombinant mouse NAMPT expressed in bacterial expression system using nicotinamide as substrate after 1 hr by fluorescence based NMNAT-3 enzyme coupled assay | Mus musculus | 39 | ALA4007408 | assay format | Scientific Literature | |
5. | ALA4008462 | Functional | Cytotoxicity against human SH-SY5Y cells assessed as reduction in cell viability after 56 hrs by MTT assay | Homo sapiens | 39 | ALA4007408 | cell-based format | Scientific Literature | |
6. | ALA4008481 | ADME | Drug metabolism in human liver microsomes assessed as pyridine N-oxidation by measuring 7-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)heptanoic acid formation after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Homo sapiens | 2 | ALA4007408 | assay format | Scientific Literature | |
7. | ALA4008482 | ADME | Drug metabolism in human liver microsomes assessed as pyridine N-oxidation by measuring biphenyl-2-carboxamide formation after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Homo sapiens | 2 | ALA4007408 | assay format | Scientific Literature | |
8. | ALA4008483 | ADME | Drug metabolism in Wistar Han rat liver microsomes assessed as pyridine N-oxidation by measuring 7-(4-(pyridin-3-yl)-1H-1,2,3-triazol-1-yl)heptanoic acid formation after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Rattus norvegicus | 2 | ALA4007408 | assay format | Scientific Literature | |
9. | ALA4008484 | ADME | Drug metabolism in Wistar Han rat liver microsomes assessed as pyridine N-oxidation by measuring biphenyl-2-carboxamide formation after 60 mins in presence of NADPH-regenerating system by LC-UV analysis | Rattus norvegicus | 2 | ALA4007408 | assay format | Scientific Literature |