| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4017129 | F | Antiproliferative activity against human A2780 cells measured after 72 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 2. | ALA4017130 | F | Antiproliferative activity against human CAL27 cells measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 3. | ALA4017131 | F | Antiproliferative activity against human A2780cisR cells measured after 72 hrs by MTT assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 4. | ALA4017132 | F | Antiproliferative activity against human Cal27CisR cells measured after 72 hrs by MTT assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 5. | ALA4017133 | F | Antiproliferative activity against human Med8A cells after 72 hrs by Celltiter-Glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 6. | ALA4017134 | F | Antiproliferative activity against human ONS76 cells after 72 hrs by Celltiter-Glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 7. | ALA4017135 | B | Inhibition of HDAC in human A2780 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 8. | ALA4017136 | B | Inhibition of HDAC in human CAL27 cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 9. | ALA4017137 | B | Inhibition of HDAC in human A2780CisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 10. | ALA4017138 | B | Inhibition of HDAC in human Cal27CisR cells using Boc-Lys(epsilon-Ac)-AMC as substrate preincubated for 18 hrs followed by substrate addition measured after 3 hrs by fluorescence assay | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
| 11. | ALA4017139 | B | Inhibition of recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells using Z-(Ac)Lys-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA4017140 | B | Inhibition of full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells Z-(Ac)Lys-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4017141 | A | Inhibition of human HDAC8 using Z-L-Lys(epsilon-trifluoroacetyl)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 14. | ALA4017142 | B | Inhibition of recombinant human N-terminal GST-tagged/C-terminal His-tagged HDAC4 expressed in insect cells using Boc-K(Ac)-AMC as substrate by fluorescence assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA4017143 | B | Selectivity index, ratio of IC50 for recombinant full length human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected sf9 cells to IC50 for full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4017144 | U | Selectivity index, ratio of IC50 for human recombinant HDAC8 to IC50 for full length human recombinant N-terminal GST-tagged HDAC6 expressed in baculovirus infected sf9 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4017145 | B | Inhibition of HDAC6 in human CAL27 cells assessed as accumulation of acetylated alpha tubulin at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA4017146 | B | Inhibition of HDAC6 in human Cal27CisR cells assessed accumulation of acetylated alpha tubulin at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4017147 | B | Inhibition of HDAC1 in human CAL27 cells assessed as accumulation of histone 3 acetylation at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA4017148 | B | Inhibition of HDAC1 in human Cal27CisR cells assessed as accumulation of histone 3 acetylation at 1 uM after 24 hrs by immunoblot analysis | Homo sapiens | 4 | cell-based format | Scientific Literature |
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