| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4053981 | B | Inhibition of chymotrypsin like activity of 26S proteasome beta 5 subunit in human U266 cells assessed as residual activity using N-Suc-LLVY-AMC as substrate at 10 uM preincubated for 1 hr followed by substrate addition and measured after 4 hrs by fluorescence assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 2. | ALA4053982 | F | Antiproliferative activity against human K562 cells after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 3. | ALA4053983 | F | Antiproliferative activity against human CEM cells after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 4. | ALA4053984 | F | Antiproliferative activity against human U266 cells after 72 hrs by calcein AM staining based fluorescence assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 5. | ALA4053985 | B | Inhibition of chymotrypsin-like activity of 26S proteasome beta 5 subunit in human U266 cells using Suc-LLVY-aminoluciferin as substrate after 1 hr by Proteosome-Glo luminescence assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 6. | ALA4053986 | B | Inhibition of trypsin like activity of 26S proteasome beta 2 subunit in human U266 cells assessed as residual activity using Z-LLE-AMC as substrate at 10 uM preincubated for 1 hr followed by substrate addition and measured after 4 hrs by fluorescence assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 7. | ALA4053987 | B | Inhibition of proteasome in human U2OS cells stably expressing GFP fused to short degron assessed as increase in GFP accumulation pre-incubated for 1 hr and measured after 9 hrs by live-cell imaging microscopy | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4053990 | B | Inhibition of caspase like activity of 26S proteasome beta 1 subunit in human U266 cells assessed as residual activity using Bz-VGR-AMC as substrate at 10 uM preincubated for 1 hr followed by substrate addition and measured after 4 hrs by fluorescence assay relative to control | Homo sapiens | 19 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!