| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4043634 | B | Inhibition of bovine GRK2 S670A mutant after 5 mins in presence of ATP by phosphorimaging assay | Bos taurus | 34 | assay format | Scientific Literature | ||
| 2. | ALA4043635 | B | Inhibition of bovine GRK1 (1 to 535 residues) after 5 mins after 5 mins in presence of ATP by phosphorimaging assay | Bos taurus | 34 | single protein format | Scientific Literature | ||
| 3. | ALA4043636 | B | Inhibition of bovine GRK5 after 5 mins after 5 mins in presence of ATP by phosphorimaging assay | Bos taurus | 34 | single protein format | Scientific Literature | ||
| 4. | ALA4043637 | B | Inhibition of mouse PKA using CREBtide as substrate after 30 mins in presence of ATP by ADP-Glo kinase assay | Mus musculus | 34 | assay format | Scientific Literature | ||
| 5. | ALA4043638 | B | Inhibition of ROCK1 (unknown origin) at 10 uM by ADP-Glo kinase assay | Homo sapiens | 34 | single protein format | Scientific Literature | ||
| 6. | ALA4043643 | A | Half life in CD-1 mouse liver microsomes at 1 uM measured up to 60 mins in presence of NADPH by LC-MS/MS analysis | Mus musculus | 13 | assay format | Scientific Literature | ||
| 7. | ALA4043644 | B | Inhibition of GRK2 in isoproterenol-stimulated C57/BL6 mouse cardiomyocytes assessed as increase in contractility by measuring cell shortening at 0.5 uM pretreated for 10 mins followed by beta-AR agonist isoproterenol addition for 2 mins | Mus musculus | 1 | assay format | Scientific Literature | ||
| 8. | ALA4043645 | B | Inhibition of GRK2 in isoproterenol-stimulated C57/BL6 mouse cardiomyocytes assessed as increase in contractility by measuring cell shortening at 1 uM pretreated for 10 mins followed by beta-AR agonist isoproterenol addition for 2 mins | Mus musculus | 2 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!