# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3999512 | B | Inverse agonist activity at GAL4-DNA binding domain-fused human ERRalpha ligand binding domain expressed in African green monkey CV1 cells assessed as decrease in receptor transcriptional activity at 10 uM after 45 hrs by luciferase reporter gene assay | Homo sapiens | 12 | ALA3997814 | cell-based format | Scientific Literature | |
2. | ALA3999513 | B | Inverse agonist activity at GAL4-DNA binding domain-fused human ERRbeta ligand binding domain expressed in African green monkey CV1 cells assessed as decrease in receptor transcriptional activity after 45 hrs by luciferase reporter gene assay | Homo sapiens | 13 | ALA3997814 | cell-based format | Scientific Literature | |
3. | ALA3999514 | B | Inverse agonist activity at GAL4-DNA binding domain-fused mouse ERRgamma ligand binding domain expressed in African green monkey CV1 cells assessed as decrease in receptor transcriptional activity after 45 hrs by luciferase reporter gene assay | Mus musculus | 13 | ALA3997814 | cell-based format | Scientific Literature | |
4. | ALA3999517 | B | Antagonist activity at human ERalpha expressed in African green monkey CV1 cells assessed as decrease in receptor transcriptional activity after 45 hrs by luciferase reporter gene assay | Homo sapiens | 1 | ALA3997814 | cell-based format | Scientific Literature | |
5. | ALA3999519 | B | Inverse agonist activity at ERRgamma (unknown origin) expressed in HEK293 cells assessed as downregulation of SHP transcript levels at 100 nM after 48 hrs by real-time PCR method | Homo sapiens | 1 | ALA3997814 | cell-based format | Scientific Literature | |
6. | ALA3999520 | B | Inverse agonist activity at ERRgamma in mouse C2C12 cells assessed as downregulation of SHP transcript levels at 100 nM after 48 hrs by real-time PCR method relative to control | Mus musculus | 1 | ALA3997814 | cell-based format | Scientific Literature | |
7. | ALA3999521 | B | Inverse agonist activity at ERRgamma in mouse C2C12 cells assessed as inhibition of [3H]-palmitate-BSA oxidation at 100 nM after 48 hrs by scintillation counting method relative to vehicle-treated control | Mus musculus | 1 | ALA3997814 | cell-based format | Scientific Literature |