# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4027109 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK cell membranes after 2 hrs | Rattus norvegicus | 23 | ALA4024764 | cell-based format | Scientific Literature | |
2. | ALA4027110 | Binding | Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK cell membranes after 2 hrs | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
3. | ALA4027111 | Binding | Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK cell membranes after 2 hrs | Rattus norvegicus | 26 | ALA4024764 | cell-based format | Scientific Literature | |
4. | ALA4027112 | Binding | Displacement of [3H]epibatidine from rat alpha3beta2 nAChR expressed in HEK cell membranes after 2 hrs | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
5. | ALA4027113 | Binding | Displacement of [3H]epibatidine from rat alpha3beta4alpha5 nAChR expressed in HEK cells after 2 hrs | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
6. | ALA4027114 | Binding | Selectivity ratio of Ki for rat alpha3beta4 nAChR expressed in HEK cells to Ki for rat alpha4beta2 nAChR expressed in HEK cells | Rattus norvegicus | 23 | ALA4024764 | cell-based format | Scientific Literature | |
7. | ALA4027115 | Binding | Selectivity ratio of Ki for rat alpha4beta4 nAChR expressed in HEK cells to Ki for rat alpha4beta2 nAChR expressed in HEK cells | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
8. | ALA4027116 | Binding | Selectivity ratio of Ki for rat alpha3beta4alpha5 nAChR expressed in HEK cells to Ki for rat alpha4beta2 nAChR expressed in HEK cells | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
9. | ALA4027117 | Binding | Antagonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as inhibition of epibatidine-induced membrane potential preincubated for 10 mins followed by epibatidine addition by fluorescence assay | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
10. | ALA4027118 | Binding | Antagonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as inhibition of Ca2+ flux | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
11. | ALA4027119 | Binding | Agonist activity at rat alpha3beta4 nAChR expressed in HEK cells assessed as induction of Ca2+ flux | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature | |
12. | ALA4027128 | Binding | Agonist activity at alpha7 nAChR (unknown origin) assessed as change in membrane potential | Homo sapiens | 2 | ALA4024764 | assay format | Scientific Literature | |
13. | ALA4027129 | Binding | Antagonist activity at alpha7 nAChR (unknown origin) assessed as inhibition of acetylcholine-induced membrane potential | Homo sapiens | 2 | ALA4024764 | assay format | Scientific Literature | |
14. | ALA4027130 | Binding | Agonist activity at rat alpha4beta2 nAChR expressed in HEK cells assessed as induction of membrane potential measured every 3 secs for 120 secs by fluorescence assay | Rattus norvegicus | 2 | ALA4024764 | cell-based format | Scientific Literature |