| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4047162 | F | Agonist activity at human CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA4047163 | F | Agonist activity at mouse CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4047164 | A | Apparent permeability of the compound in MDCK cells expressing human MRDR1 at 3 uM after 60 mins in presence of P-gp inhibitor GF120918A by LC-MS/MS analysis | Canis lupus familiaris | 19 | cell-based format | Scientific Literature | ||
| 4. | ALA4047165 | A | Half-life in Sprague-Dawley rat cecal homogenates at 10 uM by LC-MS/MS analysis | Rattus norvegicus | 19 | tissue-based format | Scientific Literature | ||
| 5. | ALA4047166 | A | Cmax in CD rat portal vein at 30 mg/kg, po administered via gavage | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 6. | ALA4047168 | A | Cmax in CD rat systemic circulation at 30 mg/kg, po administered via gavage | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA4047170 | A | Drug recovery in CD rat feces at 30 mg/kg, po administered via gavage measured by LC-MS/MS analysis | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA4047171 | A | AUC in CD rat portal vein at 10 mg/kg, po administered via gavage | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4047172 | A | AUC in CD rat systemic circulation at 10 mg/kg, po administered via gavage | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4047173 | A | Protein binding in CD rat plasma at 10 mg/kg, administered via gavage | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4047174 | A | Unbound Cmax in CD rat portal vein at 10 mg/kg, po administered via gavage | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4047175 | A | Unbound Cmax in CD rat systemic circulation at 10 mg/kg, po administered via gavage | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4047176 | F | Agonist activity at rat CaSR expressed in HEK293 cells assessed as increase in intracellular calcium mobilization by fluo-4AM dye based FLIPR assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4047177 | P | Aqueous solubility of the compound in FASSIF | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA4047178 | P | Aqueous solubility of the compound in FESSIF | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 16. | ALA4047179 | P | Aqueous solubility of the compound in SGF | 1 | small-molecule physicochemical format | Scientific Literature |
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