# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3999001 | B | Inhibition of full length recombinant His6-tagged PI4K3beta (unknown origin) expressed in Sf9 insect cells using PI : PS as substrate in presence of [gamma-33P]-ATP by scintillation counting method | Homo sapiens | 24 | ALA3997800 | cell-based format | Scientific Literature | |
2. | ALA3999002 | F | Antiviral activity against Enterovirus 71 infected in RD cells assessed as reduction in virus-induced cytopathic effect incubated for 2 to 3 days | Enterovirus A71 | 24 | ALA3997800 | cell-based format | Scientific Literature | |
3. | ALA3999003 | A | Cytotoxicity against human RD cells after 2 to 3 days by MTS method | Homo sapiens | 24 | ALA3997800 | cell-based format | Scientific Literature | |
4. | ALA3999004 | A | Cytotoxicity against human RD cells assessed as change in cell morphology by microscopic method | Homo sapiens | 24 | ALA3997800 | cell-based format | Scientific Literature | |
5. | ALA3999005 | T | Selectivity index, ratio of CC50 for human RD cells to EC50 for Enterovirus 71 | 24 | ALA3997800 | assay format | Scientific Literature | ||
6. | ALA3999006 | T | Selectivity index, ratio of CC50 for human RD cells assessed as change in cell morphology to EC50 for Enterovirus 71 | 24 | ALA3997800 | assay format | Scientific Literature | ||
7. | ALA4479297 | B | Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substrate and [32P]ATP measured after 10 mins by Kinase-Glo assay | Rattus norvegicus | 56 | ALA4477233 | assay format | Scientific Literature | |
8. | ALA4483863 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Plasmodium berghei | 9,989 | ALA4483862 | organism-based format | Winzeler Lab Plasmodium Screening Data | |
9. | ALA4483864 | F | Luciferase/luciferin-expressing antifolate-resistant parasites were used to infect a culture of HepG2 cells that were pre-incubated with compounds. Infected hepatocytes emit light due to the luciferase reaction. Assay results are presented as the percent inhibition of light emission compared to control. (Single Point Inhibition, %) | Homo sapiens | 9,989 | ALA4483862 | cell-based format | Winzeler Lab Plasmodium Screening Data | |
10. | ALA5242011 | B | Inhibition of DC-SIGN extracellular domain (unknown origin) expressed in Escherichia coli DE3(BL21) incubated for 1 hrs in presence of Man-Fl-BSA by high-throughput fluorescence-based assay | Homo sapiens | 11 | ALA5241084 | assay format | Scientific Literature |