#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4035969	P	Aqueous solubility of the compound in phosphate buffer at pH 7.4 using crystalline sample		1	ALA4033707	small-molecule physicochemical format	Scientific Literature
2.	ALA4035970	B	Inhibition of PI3Kalpha (unknown origin)	Homo sapiens	6	ALA4033707	single protein format	Scientific Literature
3.	ALA4035971	B	Inhibition of PI3Kbeta (unknown origin)	Homo sapiens	6	ALA4033707	single protein format	Scientific Literature
4.	ALA4035972	B	Inhibition of PI3Kalpha mutant in human BT474 cells assessed as reduction in AKT phosphorylation at Thr308	Homo sapiens	8	ALA4033707	cell-based format	Scientific Literature
5.	ALA4035973	B	Inhibition of PI3Kbeta in PTEN-deficient human MDA-MB-468 cells assessed as reduction in AKT phosphorylation at Ser473	Homo sapiens	8	ALA4033707	assay format	Scientific Literature
6.	ALA4035974	B	Selectivity ratio of IC50 for PI3Kbeta in PTEN-deficient human MDA-MB-468 cells to IC50 for PI3Kalpha mutant in human BT474 cells	Homo sapiens	1	ALA4033707	cell-based format	Scientific Literature
7.	ALA4035975	P	Dissociation constant, pKa of the compound		2	ALA4033707	small-molecule physicochemical format	Scientific Literature
8.	ALA4035976	P	Octanol-buffer partition coefficient, log D of the compound at pH 7.4 by shake-flask method		2	ALA4033707	small-molecule physicochemical format	Scientific Literature
9.	ALA4035978	A	Apparent permeability of the compound across apical side to basolateral side in human Caco2 cells	Homo sapiens	2	ALA4033707	cell-based format	Scientific Literature
10.	ALA4035979	A	Clearance in Han Wistar rat at 4 umol/kg, iv or 10 umol/kg, po	Rattus norvegicus	2	ALA4033707	organism-based format	Scientific Literature
11.	ALA4035980	A	Volume of distribution in Han Wistar rat at 4 umol/kg, iv or 10 umol/kg, po	Rattus norvegicus	2	ALA4033707	organism-based format	Scientific Literature
12.	ALA4035981	A	Oral bioavailability in Han Wistar rat at 10 umol/kg	Rattus norvegicus	2	ALA4033707	organism-based format	Scientific Literature
13.	ALA4035982	A	Clearance in Beagle dog at 1 umol/kg, po	Canis lupus familiaris	1	ALA4033707	assay format	Scientific Literature
14.	ALA4035983	A	Volume of distribution in Beagle dog at 1 umol/kg, po	Canis lupus familiaris	1	ALA4033707	assay format	Scientific Literature
15.	ALA4035984	A	Oral bioavailability in Beagle dog at 1 umol/kg	Canis lupus familiaris	1	ALA4033707	organism-based format	Scientific Literature
16.	ALA4035985	A	AUC in mouse at 100 mg/kg, po	Mus musculus	1	ALA4033707	organism-based format	Scientific Literature
17.	ALA4035986	A	Cmax in mouse at 100 mg/kg, po	Mus musculus	1	ALA4033707	organism-based format	Scientific Literature
18.	ALA4035987	F	Anti-tumor activity against human MCF7 cells harboring PI3KCA E545K mutant xenografted in Swiss nu/nu mouse assessed as tumor growth inhibition at 50 mg/kg, po administered twice daily for 21 days measured post last dose relative to control	Homo sapiens	1	ALA4033707	organism-based format	Scientific Literature
19.	ALA4035988	F	Anti-tumor activity against human MCF7 cells harboring PI3KCA E545K mutant xenografted in Swiss nu/nu mouse assessed as tumor growth inhibition at 25 mg/kg, po administered twice daily for 21 days measured post last dose relative to control	Homo sapiens	1	ALA4033707	organism-based format	Scientific Literature
20.	ALA4035989	F	Anti-tumor activity against human MCF7 cells harboring PI3KCA E545K mutant xenografted in Swiss nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, po administered twice daily for 21 days measured post last dose relative to control	Homo sapiens	1	ALA4033707	organism-based format	Scientific Literature