# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3995118 | A | Cytotoxicity against mouse ScN2a cells assessed as cell viability at 0.1 uM after 5 days by MTT assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
2. | ALA3995119 | A | Cytotoxicity against mouse ScN2a cells assessed as cell viability at 1 uM after 5 days by MTT assay relative to control | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA3995120 | A | Cytotoxicity against mouse ScN2a cells assessed as cell viability at 10 uM after 5 days by MTT assay relative to control | Mus musculus | 12 | cell-based format | Scientific Literature | ||
4. | ALA3995122 | B | Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as proteinase K-resistant PrPSc level at 0.1 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control | Mus musculus | 11 | assay format | Scientific Literature | ||
5. | ALA3995123 | B | Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as proteinase K-resistant PrPSc level at 1 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control | Mus musculus | 11 | assay format | Scientific Literature | ||
6. | ALA3995124 | B | Antiprion activity against mouse prion protein RML infected mouse ScN2a cells assessed as proteinase K-resistant PrPSc level at 10 uM incubated for 5 days followed by proteinase K digestion by Western blot method relative to control | Mus musculus | 11 | assay format | Scientific Literature | ||
7. | ALA3995125 | B | Antiprion activity against mouse prion protein RML infected mouse ScGT1 cells assessed as reduction in proteinase K-resistant PrPSc level incubated for 7 days followed by proteinase K digestion by ELISA | Mus musculus | 1 | assay format | Scientific Literature | ||
8. | ALA3995126 | F | Effect on cellular prion protein level in mouse N2A cells up to 10 uM incubated for 5 days by Western blot method | Mus musculus | 11 | cell-based format | Scientific Literature | ||
9. | ALA3995128 | B | Binding affinity to PrPSc aggregates in mouse prion protein RML infected mouse ScN2a cells incubated for 8 mins followed by proteinase K digestion using FITC filter by fluorescence confocal microscopic method | Mus musculus | 2 | assay format | Scientific Literature | ||
10. | ALA3995129 | B | Binding affinity to proteinase K sensitive cellular prion protein in mouse N2A cells incubated for 8 mins by fluorescence confocal microscopic method | Mus musculus | 1 | cell-based format | Scientific Literature |