# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4045540 | Binding | Inhibition of P2Y12 in human platelet rich plasma assessed as reduction in ADP-induced platelet aggregation pre-incubated before ADP addition and measured after 10 mins by Bruker spectrophotometry | Homo sapiens | 26 | ALA4043160 | assay format | Scientific Literature | |
2. | ALA4045541 | Binding | Binding affinity to P2Y12 in human platelets assessed as blocking of ADP-induced inhibition of PGE1-stimulated VASP phosphorylation by measuring remaining VASP phosphorylation level at 200 uM by CY-QUANT VASP/P2Y12 ELISA method | Homo sapiens | 26 | ALA4043160 | assay format | Scientific Literature | |
3. | ALA4045542 | Binding | Agonist activity at P2Y12 in human platelets assessed as effect on VASP phosphorylation at 200 uM by CY-QUANT VASP/P2Y12 ELISA method | Homo sapiens | 23 | ALA4043160 | assay format | Scientific Literature |