| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3998527 | F | Cytotoxicity against human CCRF-CEM cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 2. | ALA3998528 | F | Cytotoxicity against human CCRF-CEM/VBL cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 3. | ALA3998529 | F | Cytotoxicity against human HCT116 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 4. | ALA3998530 | F | Cytotoxicity against human PC3 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 5. | ALA3998531 | F | Cytotoxicity against human NCI-H460 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 6. | ALA3998532 | F | Cytotoxicity against human NCI-H526 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 7. | ALA3998533 | F | Cytotoxicity against human NCI-H211 cells assessed as decrease in cell proliferation after 72 hrs by Alamar blue assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 8. | ALA3998534 | F | Resistance factor, ratio of IC50 for human CCRF-CEM/VBL cells to IC50 for human CCRF-CEM cells | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 9. | ALA3998552 | B | Inhibition of recombinant human DNA-topoisomerase 1 assessed as decrease in supercoiled pHOT DNA relaxation at 20 uM after 30 mins by ethidium bromide staining-based agarose gel electrophoresis method | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 10. | ALA3998553 | B | Inhibition of recombinant human DNA-topoisomerase 1 assessed as decrease in supercoiled pHOT DNA relaxation at 100 uM after 30 mins by ethidium bromide staining-based agarose gel electrophoresis method | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 11. | ALA3998554 | B | Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation at 20 uM after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method relative to control | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 12. | ALA3998555 | B | Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation at 100 uM after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method relative to control | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 13. | ALA3998556 | B | Inhibition of recombinant human DNA-topoisomerase 2 assessed as decrease in supercoiled pHOT DNA relaxation after 30 to 45 mins by ethidium bromide staining-based agarose gel electrophoresis method | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 14. | ALA3998560 | B | Induction of pEGFP-N1 DNA (unknown origin) interstrand cross linking at 20 to 200 uM after 2 hrs by alkaline agarose gel shift assay | Not specified | 1 | assay format | Scientific Literature |
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