#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4057803	Binding	Inhibition of TACE in human whole blood assessed as inhibition of LPS-stimulated TNFalpha production pretreated for 1 hr followed by LPS stimulation for 3.5 hrs by ELISA	Homo sapiens	18	ALA4052764	single protein format	Scientific Literature
2.	ALA4057805	ADME	AUC in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 10 mg/kg, po by HPLC/MS analysis	Rattus norvegicus	17	ALA4052764	organism-based format	Scientific Literature
3.	ALA4057806	ADME	AUC in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 100 mg/kg, po administered as single dose by LC/MS/MS analysis	Rattus norvegicus	1	ALA4052764	organism-based format	Scientific Literature
4.	ALA4057807	ADME	AUC in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 300 mg/kg, po administered as single dose by LC/MS/MS analysis	Rattus norvegicus	1	ALA4052764	organism-based format	Scientific Literature
5.	ALA4057808	ADME	AUC in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 500 mg/kg, po administered as single dose by LC/MS/MS analysis	Rattus norvegicus	1	ALA4052764	organism-based format	Scientific Literature
6.	ALA4057810	ADME	Permeability in human Caco2 cells at pH 7.4	Homo sapiens	2	ALA4052764	cell-based format	Scientific Literature
7.	ALA4057811	Physicochemical	Solubility of the compound at pH 6.5		2	ALA4052764	small-molecule physicochemical format	Scientific Literature
8.	ALA4057812	ADME	Oral bioavailability in rat assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level at 10 mg/kg by LC/MS/MS analysis	Rattus norvegicus	1	ALA4052764	organism-based format	Scientific Literature
9.	ALA4057813	ADME	Oral bioavailability in monkey assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level by LC/MS/MS analysis	Macaca mulatta	1	ALA4052764	organism-based format	Scientific Literature
10.	ALA4057814	ADME	Oral bioavailability in dog assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione level by LC/MS/MS analysis	Canis lupus familiaris	1	ALA4052764	organism-based format	Scientific Literature
11.	ALA4057815	ADME	Prodrug activation in human intestinal microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Homo sapiens	1	ALA4052764	assay format	Scientific Literature
12.	ALA4057816	ADME	Prodrug activation in mouse liver microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Mus musculus	1	ALA4052764	assay format	Scientific Literature
13.	ALA4057817	ADME	Prodrug activation in rat liver microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Rattus norvegicus	1	ALA4052764	assay format	Scientific Literature
14.	ALA4057818	ADME	Prodrug activation in dog liver microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Canis lupus familiaris	1	ALA4052764	assay format	Scientific Literature
15.	ALA4057819	ADME	Prodrug activation in monkey liver microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Macaca mulatta	1	ALA4052764	assay format	Scientific Literature
16.	ALA4057820	ADME	Prodrug activation in human liver microsomes assessed as (S)-5-(furo[3,2-b]pyridin-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione formation	Homo sapiens	1	ALA4052764	assay format	Scientific Literature