# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4052870 | A | Drug uptake in human MDA-MB-231 cells assessed per million cells at 2 uM in presence of 10% FBS after 24 hrs incubation by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
2. | ALA4052873 | F | Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTS assay | Homo sapiens | 4 | ALA4052582 | cell-based format | Scientific Literature | |
3. | ALA4052878 | A | Drug uptake in human MDA-MB-231 cells assessed per million cells at 2 uM in presence of 1% FBS after 24 hrs incubation by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
4. | ALA4052879 | A | Drug uptake in human MDA-MB-231 cells assessed per million cells at 2 uM in presence of 5% FBS after 24 hrs incubation by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
5. | ALA4052883 | A | Drug accumulation in human MDA-MB-231 cells at 2 uM in presence of 5% FBS after 24 hrs incubation by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
6. | ALA4052884 | A | Drug uptake in human MDA-MB-231 cells assessed per million cells preincubated for 6 hrs followed by solvent addition measured after overnight incubation at 4 degC by HPLC-MS analysis | Homo sapiens | 4 | ALA4052582 | cell-based format | Scientific Literature | |
7. | ALA4052885 | A | Drug uptake in human MDA-MB-231 cells assessed per million cells preincubated for 6 hrs followed by trypsin-EDTA digestion for 2 mins measured after overnight incubation at 4 degC by HPLC-MS analysis | Homo sapiens | 4 | ALA4052582 | cell-based format | Scientific Literature | |
8. | ALA4052886 | A | Drug uptake in human MDA-MB-231 cells assessed as cell bound drug level per million cells at 2 uM in presence of 5% FBS after 6 hrs at 4 degC by HPLC-MS analysis | Homo sapiens | 8 | ALA4052582 | cell-based format | Scientific Literature | |
9. | ALA4052887 | P | Apparent permeability at 200 uM after 5 hrs by PAMPA | 4 | ALA4052582 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4052888 | P | Permeability assessed as drug transport at 200 uM after 5 hrs by PAMPA | 4 | ALA4052582 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA4052891 | P | Solubility of the compound in DMEM medium up to 200 uM | 4 | ALA4052582 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4052892 | P | Solubility of the compound in water | 4 | ALA4052582 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4052893 | U | Stability of the compound in DMEM medium assessed as parent compound remaining at 100 uM after 72 hrs in absence of 10% FBS by HPLC method | 4 | ALA4052582 | assay format | Scientific Literature | ||
14. | ALA4052894 | U | Stability of the compound in DMEM medium assessed as parent compound remaining at 100 uM after 72 hrs in presence of 10% FBS by HPLC method | 4 | ALA4052582 | assay format | Scientific Literature | ||
15. | ALA4052897 | U | Retention time of the compound by HPLC/DAD analysis | 4 | ALA4052582 | assay format | Scientific Literature | ||
16. | ALA4052901 | A | Drug uptake in human MDA-MB-231 cells assessed as intracellular concentration at 0.0103 umol in presence of 5% FBS after 24 hrs by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
17. | ALA4052904 | A | Drug recovery in human MDA-MB-231 cells at 0.0103 umol in presence of 5% FBS after 24 hrs by HPLC-MS analysis | Homo sapiens | 1 | ALA4052582 | cell-based format | Scientific Literature | |
18. | ALA4052909 | A | Drug uptake in human MDA-MB-231 cells assessed as extracted concentration at 2 uM after 24 hrs by HPLC-MS analysis | Homo sapiens | 3 | ALA4052582 | cell-based format | Scientific Literature | |
19. | ALA4052910 | A | Drug uptake in human MDA-MB-231 cells assessed as extracted concentration at 20 uM after 24 hrs by HPLC-MS analysis | Homo sapiens | 3 | ALA4052582 | cell-based format | Scientific Literature | |
20. | ALA4052912 | A | Drug uptake in human MDA-MB-231 cells assessed as extracted concentration at 0.2 uM after 24 hrs by HPLC-MS analysis | Homo sapiens | 2 | ALA4052582 | cell-based format | Scientific Literature |