# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4007514 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by SRB assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
2. | ALA4007515 | Functional | Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by SRB assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
3. | ALA4007516 | Functional | Cytotoxicity against human SW1990 cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by SRB assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
4. | ALA4007517 | Functional | Cytotoxicity against human HeLa cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by SRB assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
5. | ALA4007518 | Functional | Cytotoxicity against human Raji cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
6. | ALA4007519 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability at 10 uM measured after 72 hrs by SRB assay relative to control | Homo sapiens | 13 | ALA4007381 | cell-based format | Scientific Literature | |
7. | ALA4007520 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
8. | ALA4007521 | Functional | Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
9. | ALA4007522 | Functional | Cytotoxicity against human SW1990 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
10. | ALA4007523 | Functional | Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
11. | ALA4007524 | Functional | Cytotoxicity against human Raji cells assessed as reduction in cell viability measured after 72 hrs by MTT assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
12. | ALA4007525 | Functional | Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4007381 | cell-based format | Scientific Literature | |
13. | ALA4007526 | Functional | Cell cycle arrest in human SKOV3 cells assessed as accumulation at G0/G1 phase at 3 uM measured after 48 hrs by propidium iodide staining-based FACS analysis (Rvb = 49.47 +/- 1.91%) | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
14. | ALA4007527 | Functional | Cell cycle arrest in human SKOV3 cells assessed as accumulation at S phase at 3 uM measured after 48 hrs by propidium iodide staining-based FACS analysis(Rvb = 37.31 +/- 3.48%) | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
15. | ALA4007530 | Functional | Cell cycle arrest in human SKOV3 cells assessed as decrease in accumulation at G2/M phase at 3 uM measured after 48 hrs by propidium iodide staining-based FACS analysis | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
16. | ALA4007532 | Functional | Induction of apoptosis in human SKOV3 cells assessed as upregulation of caspase3 expression at 3 uM measured after 24 to 48 hrs by Hoechst-33342 staining-based immunofluorescent analysis relative to DMSO-control | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
17. | ALA4007533 | Functional | Induction of apoptosis in human SKOV3 cells assessed as upregulation of p53 expression at 3 uM measured after 24 to 48 hrs by Hoechst-33342 staining-based immunofluorescent analysis relative to DMSO-control | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
18. | ALA4007534 | Functional | Induction of apoptosis in human SKOV3 cells assessed as downregulation of Bcl2 expression at 3 uM measured after 24 to 48 hrs by Hoechst-33342 staining-based immunofluorescent analysis relative to DMSO-control | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
19. | ALA4007535 | Functional | Induction of apoptosis in human SKOV3 cells assessed as effect on Bax expression at 3 uM measured after 24 to 48 hrs by Hoechst-33342 staining-based immunofluorescent analysis relative to DMSO-control | Homo sapiens | 1 | ALA4007381 | cell-based format | Scientific Literature | |
20. | ALA4734464 | Functional | Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth at 10 uM measured after 72 hrs by MTT assay relative to control | Homo sapiens | 21 | ALA4732096 | cell-based format | Scientific Literature |