# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4001001 | A | Metabolic stability in human serum assessed as parent compound remaining after 6 hrs by UPLC method | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
2. | ALA4001002 | B | Inhibition of bovine beta-trypsin up to 100 uM using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by spectrometric method | Bos taurus | 4 | single protein format | Scientific Literature | ||
3. | ALA4001003 | A | Cytotoxicity against human HeLa cells up to 40 uM after 24 hrs by PrestoBlue cell viability assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
4. | ALA4001004 | F | Antagonist activity against bradykinin B1 receptor in human HeLa cells assessed as inhibition of Des-Arg9-BK-induced increase in intracellular Ca2+ level by Fluro-4 direct calcium dye based fluorescence assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
5. | ALA4001007 | P | Stability in pH 7 phosphate buffer at 0.1 mM at 100 degC after 6 hrs by HPLC-MS analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA4001008 | P | Stability in 0.2 M aqueous HCl after 6 hrs by HPLC-MS analysis | 6 | small-molecule physicochemical format | Scientific Literature | |||
7. | ALA4001009 | A | Stability of the compound assessed as trypsin (unknown origin)-mediated compound degradation at enzyme to peptide ratio of 1:50 after 6 hrs by HPLC-MS analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
8. | ALA4001010 | A | Stability of the compound assessed as pepsin (unknown origin)-mediated compound degradation at enzyme to peptide ratio of 1:50 after 6 hrs by HPLC-MS analysis | Homo sapiens | 5 | assay format | Scientific Literature |