# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4046546 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 50 ug/ml after 24 hrs by MTT assay | Mus musculus | 18 | ALA4043186 | cell-based format | Scientific Literature | |
2. | ALA4046547 | A | Cytotoxicity against mouse RAW264.7 cells assessed as reduction in cell viability at 50 ug/ml preincubated for 24 hrs followed by LPS induction measured after 18 hrs by MTT assay | Mus musculus | 12 | ALA4043186 | cell-based format | Scientific Literature | |
3. | ALA4046548 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as decrease in LPS-stimulated TNFalpa release after 24 hrs by ELISA | Mus musculus | 2 | ALA4043186 | cell-based format | Scientific Literature | |
4. | ALA4046549 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as LPS-stimulated TNFalpa release at 50 ug/ml after 24 hrs by ELISA relative to LPS-treated control | Mus musculus | 2 | ALA4043186 | cell-based format | Scientific Literature | |
5. | ALA4046550 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as LPS-stimulated IL6 release at 12.5 ug/ml after 24 hrs by ELISA relative to LPS-treated control | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
6. | ALA4046551 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as LPS-stimulated IL6 release at 25 ug/ml after 24 hrs by ELISA relative to LPS-treated control | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
7. | ALA4046552 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as LPS-stimulated IL6 release at 50 ug/ml after 24 hrs by ELISA relative to LPS-treated control | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
8. | ALA4046553 | F | Antiinflammatory activity in Kunming mouse assessed as inhibition of xylene-induced ear edema at 12.5 mg/kg, ip pretreated for 30 mins followed by xylene challenge measured after 30 mins relative to control | Mus musculus | 2 | ALA4043186 | organism-based format | Scientific Literature | |
9. | ALA4046554 | F | Antiinflammatory activity in Kunming mouse assessed as inhibition of xylene-induced ear edema at 25 mg/kg, ip pretreated for 30 mins followed by xylene challenge measured after 30 mins relative to control | Mus musculus | 2 | ALA4043186 | organism-based format | Scientific Literature | |
10. | ALA4046555 | F | Antiinflammatory activity in Kunming mouse assessed as inhibition of xylene-induced ear edema at 50 mg/kg, ip pretreated for 30 mins followed by xylene challenge measured after 30 mins relative to control | Mus musculus | 4 | ALA4043186 | organism-based format | Scientific Literature | |
11. | ALA4046556 | B | Inhibition of ERK phosphorylation in mouse RAW264.7 cells incubated for 24 hrs followed by LPS-stimulation measured after 24 hrs by Western blot method | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
12. | ALA4046557 | B | Inhibition of p38 phosphorylation in mouse RAW264.7 cells incubated for 24 hrs followed by LPS-stimulation measured after 24 hrs by Western blot method | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
13. | ALA4046558 | B | Inhibition of LPS-induced NFkappaB activation in mouse RAW264.7 cells assessed as reduction p65 phosphorylation at 12.5 to 50 ug/ml preincubated for 24 hrs followed by LPS-stimulation measured after 24 hrs by Western blot method | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
14. | ALA4046559 | B | Inhibition of NFkappaB in mouse RAW264.7 cells assessed as decrease in LPS-induced degradation of IkappaB preincubated for 24 hrs followed by LPS-stimulation measured after 24 hrs by Western blot method | Mus musculus | 1 | ALA4043186 | cell-based format | Scientific Literature | |
15. | ALA4046560 | B | Inhibition of COX-2 (unknown origin) assessed as protein/GADPH ratio at 50 ug/ml relative to control | Homo sapiens | 1 | ALA4043186 | single protein format | Scientific Literature | |
16. | ALA4046561 | F | Antiinflammatory activity against mouse RAW264.7 cells assessed as decrease in LPS-stimulated IL-6 release after 24 hrs by ELISA | Mus musculus | 2 | ALA4043186 | cell-based format | Scientific Literature |