| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4052045 | B | Inhibition of recombinant rat nNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Rattus norvegicus | 21 | assay format | Scientific Literature | ||
| 2. | ALA4052046 | B | Inhibition of recombinant human full-length nNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 3. | ALA4052047 | A | Inhibition of recombinant mouse macrophage iNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of 10 uM H4B by hemoglobin capture assay | Mus musculus | 21 | assay format | Scientific Literature | ||
| 4. | ALA4052048 | A | Inhibition of recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 5. | ALA4052049 | U | Selectivity ratio of Ki for recombinant mouse macrophage iNOS expressed in Escherichia coli to Ki for recombinant rat nNOS expressed in Escherichia coli | 21 | assay format | Scientific Literature | |||
| 6. | ALA4052050 | U | Selectivity ratio of Ki for recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) to Ki for recombinant human full-length nNOS expressed in Escherichia coli BL21(DE3) | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 7. | ALA5252150 | F | Cytotoxicity against human A-375 cells by MTT colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA5252151 | F | Cytotoxicity against human E297 cells by MTT colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA5252152 | T | Cytotoxicity against HEK293 cells by MTT colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA5252153 | F | Cytotoxicity against human HepG2 cells by MTT colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5252154 | T | Toxicity in mouse at 10 mg/kg measured after 21 days | Mus musculus | 1 | organism-based format | Scientific Literature |
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