# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4052045 | Binding | Inhibition of recombinant rat nNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Rattus norvegicus | 21 | ALA4049447 | assay format | Scientific Literature | |
2. | ALA4052046 | Binding | Inhibition of recombinant human full-length nNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Homo sapiens | 21 | ALA4049447 | assay format | Scientific Literature | |
3. | ALA4052047 | ADME | Inhibition of recombinant mouse macrophage iNOS expressed in Escherichia coli assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of 10 uM H4B by hemoglobin capture assay | Mus musculus | 21 | ALA4049447 | assay format | Scientific Literature | |
4. | ALA4052048 | ADME | Inhibition of recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) assessed as reduction in nitric oxide production using L-arginine as substrate measured for 5 mins in presence of calmodulin/10 uM H4B by hemoglobin capture assay | Homo sapiens | 21 | ALA4049447 | assay format | Scientific Literature | |
5. | ALA4052049 | Unassigned | Selectivity ratio of Ki for recombinant mouse macrophage iNOS expressed in Escherichia coli to Ki for recombinant rat nNOS expressed in Escherichia coli | 21 | ALA4049447 | assay format | Scientific Literature | ||
6. | ALA4052050 | Unassigned | Selectivity ratio of Ki for recombinant human full-length eNOS expressed in Escherichia coli BL21(DE3) to Ki for recombinant human full-length nNOS expressed in Escherichia coli BL21(DE3) | Homo sapiens | 21 | ALA4049447 | assay format | Scientific Literature | |
7. | ALA5252150 | Functional | Cytotoxicity against human A-375 cells by MTT colorimetric assay | Homo sapiens | 1 | ALA5247665 | cell-based format | Scientific Literature | |
8. | ALA5252151 | Functional | Cytotoxicity against human E297 cells by MTT colorimetric assay | Homo sapiens | 1 | ALA5247665 | cell-based format | Scientific Literature | |
9. | ALA5252152 | Toxicity | Cytotoxicity against HEK293 cells by MTT colorimetric assay | Homo sapiens | 1 | ALA5247665 | cell-based format | Scientific Literature | |
10. | ALA5252153 | Functional | Cytotoxicity against human HepG2 cells by MTT colorimetric assay | Homo sapiens | 1 | ALA5247665 | cell-based format | Scientific Literature | |
11. | ALA5252154 | Toxicity | Toxicity in mouse at 10 mg/kg measured after 21 days | Mus musculus | 1 | ALA5247665 | organism-based format | Scientific Literature |