| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4030011 | B | Inhibition of human ROMK channel expressed in HEK293 cells after 30 mins by FLIPR based thallium flux assay | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 2. | ALA4030012 | B | Displacement of [35S]MK499 from human ERG expressed in HEK293 cells | Homo sapiens | 47 | cell-based format | Scientific Literature | ||
| 3. | ALA4030013 | B | Selectivity ratio of IC50 for human ERG expressed in HEK293 cells to IC50 for human ROMK expressed in HEK293 cells | Homo sapiens | 37 | cell-based format | Scientific Literature | ||
| 4. | ALA4030020 | F | Antihypertensive activity in rat spontaneous hypertensive model assessed as change in systolic blood pressure at 3 mg/kg, po qd measured after 3 days | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 5. | ALA4030022 | A | Clearance in Wistar Han rat at 0.5 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 6. | ALA4030023 | A | Volume of distribution at steady state in Wistar Han rat at 0.5 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 7. | ALA4030024 | A | Dose normalized AUC in Wistar Han rat at 1 mg/kg, po | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 8. | ALA4030025 | A | Half life in Wistar Han rat at 0.5 mg/kg, iv or 1 mg/kg, po | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 9. | ALA4030026 | A | Oral bioavailability in Wistar Han rat at 1 mg/kg | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 10. | ALA4030032 | B | Inhibition of human ROMK expressed in CHO cells at -70 mV holding potential after 6 mins by whole cell patch clamp Qpatch method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA4030033 | B | Inhibition of human ERG by Qpatch electrophysiology method | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 12. | ALA4030034 | B | Selectivity ratio of IC50 for human ERG to IC50 for human ROMK expressed in CHO cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 13. | ALA4030057 | F | Antihypertensive activity in rat spontaneous hypertensive model assessed as induction of kaliuresis at 3 mg/kg, po qd measured after 3 days | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 14. | ALA4030058 | F | Antihypertensive activity in rat spontaneous hypertensive model assessed as induction of natriuresis at 3 mg/kg, po qd measured after 3 days | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 15. | ALA4030059 | A | Clearance in Beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 16. | ALA4030060 | A | Volume of distribution at steady state in Beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 17. | ALA4030061 | A | Half life in Beagle dog at 1 mg/kg, iv | Canis lupus familiaris | 3 | organism-based format | Scientific Literature | ||
| 18. | ALA4030064 | F | Antihypertensive activity in rat spontaneous hypertensive model assessed as induction of diuresis at 3 mg/kg, po qd measured after 3 days | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
| 19. | ALA5039907 | B | Inhibition of human ROMK expressed in CHO cells by whole cell voltage clamp electrophysiology assay | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 20. | ALA5039908 | T | Inhibition of human ERG expressed in HEK-293 cells by voltage clamp electrophysiology assay | Homo sapiens | 14 | cell-based format | Scientific Literature |
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