| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4053342 | F | Disruption of membrane in Staphylococcus aureus isolate DM4001R assessed as increase in ATP leakage at 4 times MIC after 1 hr by ATP bioluminescent assay relative to control | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 2. | ALA4053344 | F | Disruption of cytoplasmic membrane in Staphylococcus aureus isolate DM4001R at 2 times MIC after 3000 secs by SYTOX green dye based fluorescence assay | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 3. | ALA4053345 | B | Induction of membrane damage in DOPC/cholesterol large unilamellar vesicles assessed as calcein leakage at compound to lipid ratio of 1:16 after 1 hr by fluorescence assay relative to control | 5 | assay format | Scientific Literature | |||
| 4. | ALA4053346 | B | Induction of membrane damage in DOPE/DOPG large unilamellar vesicles assessed as calcein leakage at compound to lipid ratio of 1:16 after 1 hr by fluorescence assay relative to control | 5 | assay format | Scientific Literature | |||
| 5. | ALA4053347 | A | Cytotoxicity against human corneal fibroblasts assessed as reduction in cell viability at 100 uM after 4 hrs by CytoTox-ONE reagent-based LDH assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4053348 | A | Cytotoxicity against human corneal fibroblasts assessed as reduction in cell viability up to 250 uM after 4 hrs by CytoTox-ONE reagent-based LDH assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4053349 | F | Antibacterial activity against Staphylococcus aureus ATCC 29213 at 0.5 times MIC after 30 serial passages | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 8. | ALA4053352 | F | Bactericidal activity against methicillin-resistant Staphylococcus aureus DM21455 assessed as log reduction in bacterial load at 2 times MIC after 30 mins by time kill assay | Staphylococcus aureus | 1 | assay format | Scientific Literature | ||
| 9. | ALA4053354 | F | Bactericidal activity against methicillin-resistant Staphylococcus aureus DM21455 assessed as log reduction in bacterial load at 4 times MIC after 10 mins by time kill assay | Staphylococcus aureus | 2 | assay format | Scientific Literature | ||
| 10. | ALA4053355 | P | Solubility of the compound in water | 2 | small-molecule physicochemical format | Scientific Literature | |||
| 11. | ALA4053356 | F | Antibacterial activity against Enterococcus hirae ATCC 9790 after 24 hrs by two fold dilution assay | Enterococcus hirae ATCC 9790 | 3 | assay format | Scientific Literature | ||
| 12. | ALA4053357 | F | Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by two fold dilution assay | Enterococcus faecalis | 3 | assay format | Scientific Literature | ||
| 13. | ALA4053358 | F | Antibacterial activity against vancomycin A-resistant Enterococcus faecium VRE 1008 after 24 hrs by two fold dilution assay | Enterococcus faecium | 3 | assay format | Scientific Literature | ||
| 14. | ALA4053359 | F | Antibacterial activity against vancomycin A-resistant Enterococcus faecium VRE 1007 after 24 hrs by two fold dilution assay | Enterococcus faecium | 3 | assay format | Scientific Literature | ||
| 15. | ALA4053360 | F | Antibacterial activity against vancomycin A-resistant Enterococcus faecium VRE 1006 after 24 hrs by two fold dilution assay | Enterococcus faecium | 3 | assay format | Scientific Literature | ||
| 16. | ALA4053361 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC BAA-38 after 24 hrs by two fold dilution assay | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 17. | ALA4053362 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 700699 after 24 hrs by two fold dilution assay | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 18. | ALA4053363 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 43300 after 24 hrs by two fold dilution assay | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 19. | ALA4053364 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus DB57964 after 24 hrs by two fold dilution assay | Staphylococcus aureus | 3 | assay format | Scientific Literature | ||
| 20. | ALA4053365 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus DB68004 after 24 hrs by two fold dilution assay | Staphylococcus aureus | 3 | assay format | Scientific Literature |
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