| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4059044 | B | Binding affinity to human full length recombinant HuR expressed in Escherichia coli Rosetta DH5alpha measured for 30 mins by DMR analysis | Homo sapiens | 1 | ALA4052824 | assay format | Scientific Literature | |
| 2. | ALA4059045 | B | Binding affinity to human recombinant HuR RRM1-2 domain expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction with 5'-DY681-labeled AU-rich RNA probe at 0.3 to 10 uM after 30 mins by REMSA | Homo sapiens | 1 | ALA4052824 | assay format | Scientific Literature | |
| 3. | ALA4059046 | B | Binding affinity to human full length recombinant His-tagged HuR expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction with single-strand Bi-AU RNA probe by AlphaScreen assay | Homo sapiens | 17 | ALA4052824 | assay format | Scientific Literature | |
| 4. | ALA4059048 | B | Binding affinity to TNF AU-rich elements (unknown origin) at 10 uM by CD spectroscopic method | Not specified | 1 | ALA4052824 | assay format | Scientific Literature | |
| 5. | ALA4059049 | B | Binding affinity to 5'-DY681-labeled AU-rich RNA probe (unknown origin) at 5 uM after 30 mins by REMSA | Not specified | 1 | ALA4052824 | assay format | Scientific Literature | |
| 6. | ALA4059050 | B | Binding affinity to human recombinant HuR RRM3 domain expressed in Escherichia coli Rosetta DH5alpha assessed as inhibition of interaction with 5'-DY681-labeled AU-rich RNA probe at 0.3 to 10 uM after 30 mins by REMSA | Homo sapiens | 1 | ALA4052824 | assay format | Scientific Literature | |
| 7. | ALA4059051 | B | Inhibition of HuR-ERBB2 mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by RNA immunoprecipitation assay | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 8. | ALA4059052 | B | Inhibition of HuR-CTNNB1 mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by RNA immunoprecipitation assay | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 9. | ALA4059053 | B | Inhibition of HuR-VEGF mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by RNA immunoprecipitation assay | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 10. | ALA4059054 | B | Inhibition of HuR-ERBB2 mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 11. | ALA4059055 | B | Inhibition of HuR-CTNNB1 mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 12. | ALA4059056 | B | Inhibition of HuR-VEGF mRNA interaction in human MCF7 cells at 5 uM after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 13. | ALA4059057 | F | Downregulation of RPLP0 mRNA expression in human MCF7 cells at 5 uM after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 14. | ALA4059058 | F | Downregulation of HPRT1 mRNA expression in human MCF7 cells at 5 uM after 6 hrs by qRT-PCR method | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature | |
| 15. | ALA4059059 | B | Stabilization of closed conformation of human full length recombinant HuR RRM1-RRM2 domain at 0.6 equiv by 2D 1H 15N HSQC spectra analysis | Homo sapiens | 1 | ALA4052824 | single protein format | Scientific Literature | |
| 16. | ALA4059060 | B | Change in HuR localization from nucleus to cytoplasm in human MCF7 cells at 10 uM after 3 hrs by DAPI staining-based immunofluorescence method | Homo sapiens | 5 | ALA4052824 | cell-based format | Scientific Literature | |
| 17. | ALA4059062 | F | Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by OZBlue assay | Homo sapiens | 5 | ALA4052824 | cell-based format | Scientific Literature | |
| 18. | ALA4059063 | F | Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 72 hrs by OZBlue assay | Homo sapiens | 5 | ALA4052824 | cell-based format | Scientific Literature | |
| 19. | ALA4059064 | F | Cytotoxicity against human PANC1 cells assessed as decrease in cell viability after 72 hrs by OZBlue assay | Homo sapiens | 5 | ALA4052824 | cell-based format | Scientific Literature | |
| 20. | ALA4059065 | F | Antimigratory activity in human PANC1 cells at 5 to 20 uM after 24 to 48 hrs by scratch assay | Homo sapiens | 1 | ALA4052824 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!