| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4021718 | B | Chaperone activity at FLAG/GFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as increase in localization of protein mutant in late endosomes after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 28 | cell-based format | Scientific Literature | ||
| 2. | ALA4021721 | B | Stabilization of FLAG/GFP-tagged NPC1 I1061T mutant (unknown origin) expressed in HEK293 cells assessed as up regulation of NPC1 I1061T mutant expression after 24 hrs by Hoechst 33342 staining based fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4021722 | B | Stabilization of FLAG/GFP-tagged human NPC1L1 L1072T/I1168T double mutant expressed in HEK293 cells assessed as up regulation of NPC1L1 L1072T/I1168T double mutant expression at 3 to 30 uM after 24 hrs fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4021727 | B | Chaperone activity at FLAG/GFP-tagged human NPC1L1 L1072T/I1168T double mutant expressed in HEK293 cells assessed as localization of protein mutant in plasma membrane at 10 uM after 24 hrs fluorescence microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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