# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4027941 | B | Inhibition of recombinant bacterial VIM-2 expressed in Escherichia coli BL21 (DE3) cells using FC4 as substrate preincubated for 10 mins prior to substrate addition in presence of Triton X-100 by fluorescence-based assay | Bacteria | 17 | cell-based format | Scientific Literature | ||
2. | ALA4027944 | B | Inhibition of recombinant bacterial NDM-1 expressed in Escherichia coli BL21 (DE3) cells using imipenem as substrate in presence of Triton X-100 by spectrophotometric analysis | Bacteria | 15 | cell-based format | Scientific Literature | ||
3. | ALA4027945 | B | Inhibition of recombinant bacterial IMP-1 expressed in Escherichia coli BL21 (DE3) cells using FC4 as substrate preincubated for 10 mins prior to substrate addition in presence of Triton X-100 by fluorescence-based assay | Bacteria | 15 | cell-based format | Scientific Literature | ||
4. | ALA4027947 | B | Binding affinity to recombinant bacterial VIM-2 expressed in Escherichia coli BL21 (DE3) cells by NMR method | Bacteria | 2 | cell-based format | Scientific Literature | ||
5. | ALA4027951 | B | Inhibition of human DCLRE1A | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA4027952 | B | Inhibition of human DCLRE1B | Homo sapiens | 3 | single protein format | Scientific Literature | ||
7. | ALA4027953 | P | Aqueous solubility of the compound in phosphate buffer at pH 7.0 | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA4027954 | A | Drug metabolism in human liver microsomes | Homo sapiens | 1 | assay format | Scientific Literature | ||
9. | ALA4027955 | B | Inhibition of NDM-1 in Escherichia coli MG1655 assessed as potentiation of meropenem induced antibacterial activity by measuring meropenem MIC at 100 ug/ml after 18 to 24 hrs by broth microdilution method (Rvb = >128 ug/ml) | Escherichia coli str. K-12 substr. MG1655 | 8 | assay format | Scientific Literature | ||
10. | ALA4027956 | B | Inhibition of NDM-1 in Klebsiella pneumoniae ATCC 5055 assessed as potentiation of meropenem induced antibacterial activity by measuring meropenem MIC at 100 ug/ml after 18 to 24 hrs by broth microdilution method (Rvb = >128 ug/ml) | Klebsiella pneumoniae | 8 | single protein format | Scientific Literature |