# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4024931 | Binding | Inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as substrate pretreated for 60 mins followed by substrate addition after 1 hr by ADP-Glo luminescence assay | Homo sapiens | 49 | ALA4024706 | cell-based format | Scientific Literature | |
2. | ALA4024940 | Functional | Growth inhibition of human SU-DHL-2 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
3. | ALA4024941 | Functional | Growth inhibition of human MV411 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
4. | ALA4024942 | Functional | Growth inhibition of human U2932 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
5. | ALA4024943 | Functional | Growth inhibition of human Ramos cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
6. | ALA4024944 | Functional | Growth inhibition of human OCI-AML3 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
7. | ALA4024945 | Functional | Growth inhibition of human Pfeiffer cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
8. | ALA4024946 | Functional | Growth inhibition of human U937 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
9. | ALA4024947 | Functional | Growth inhibition of human NB4 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
10. | ALA4024948 | Functional | Growth inhibition of human SKM1 cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
11. | ALA4024949 | Functional | Growth inhibition of human M07e cells | Homo sapiens | 6 | ALA4024706 | cell-based format | Scientific Literature | |
12. | ALA4024950 | ADME | Cytotoxicity against PBMC (unknwon origin) | Not specified | 5 | ALA4024706 | cell-based format | Scientific Literature | |
13. | ALA4024953 | Binding | Effect on BTK transphosphorylation at PLCgamma1 Y783 in human U2932 cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
14. | ALA4024954 | Binding | Effect on BTK transphosphorylation at PLCgamma2 Y759 in human U2932 cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
15. | ALA4024955 | Binding | Inhibition of BTK transphosphorylation at PLCgamma2 Y1217 in human U2932 cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
16. | ALA4024958 | Binding | Effect on BTK transphosphorylation at PLCgamma1 Y783 in human Pfeiffer cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
17. | ALA4024959 | Binding | Effect on BTK transphosphorylation at PLCgamma2 Y759 in human Pfeiffer cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
18. | ALA4024960 | Binding | Inhibition of BTK transphosphorylation at PLCgamma2 Y1217 in human Pfeiffer cells up to 1 uM measured after 4 hrs by chemiluminescent assay | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
19. | ALA4024965 | Functional | Cell cycle arrest in human Pfeiffer cells assessed as increase in accumulation at G0/G1 phase at 10 uM after 48 hrs by propidium iodide/RNase staining based flow cytometric method | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature | |
20. | ALA4024966 | Functional | Cell cycle arrest in human U2932 cells assessed as increase in accumulation at G0/G1 phase at 10 uM after 48 hrs by propidium iodide/RNase staining based flow cytometric method | Homo sapiens | 3 | ALA4024706 | cell-based format | Scientific Literature |