# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4033548 | ADME | Enzymatic stability of the compound in rat plasma assessed observed rate constant | Rattus norvegicus | 1 | ALA4028917 | cell-free format | Scientific Literature | |
2. | ALA4033549 | Binding | Displacement of [3H]-(+)-pentazocine from sigma1 receptor in guinea pig brain membrane after 150 mins by liquid scintillation counting method | Cavia porcellus | 18 | ALA4028917 | cell membrane format | Scientific Literature | |
3. | ALA4033550 | Binding | Displacement of [3H]-(+)-DTG from sigma2 receptor in guinea pig brain membrane after 120 mins by liquid scintillation counting method | Cavia porcellus | 17 | ALA4028917 | cell membrane format | Scientific Literature | |
4. | ALA4033553 | Binding | Selectivity index, ratio of Ki for sigma2 receptor in guinea pig brain membrane to Ki for sigma2 receptor in guinea pig brain membrane | Cavia porcellus | 17 | ALA4028917 | cell membrane format | Scientific Literature | |
5. | ALA4033554 | Physicochemical | Aqueous solubility of the compound | 1 | ALA4028917 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4033555 | Physicochemical | Chemical stability of the compound at pH 1.3 assessed as half life | 1 | ALA4028917 | small-molecule physicochemical format | Scientific Literature | ||
7. | ALA4033556 | Physicochemical | Chemical stability of the compound at pH 7.4 assessed as half life | 1 | ALA4028917 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA4033557 | Physicochemical | Chemical stability at pH 1.3 assessed as observed rate constant | 1 | ALA4028917 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA4033558 | Physicochemical | Chemical stability at pH 7.4 assessed as observed rate constant | 1 | ALA4028917 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA4033559 | ADME | Enzymatic stability of the compound in rat plasma assessed as half life | Rattus norvegicus | 1 | ALA4028917 | cell-free format | Scientific Literature | |
11. | ALA4033560 | ADME | Enzymatic stability of the compound in mouse plasma assessed as half life | Mus musculus | 1 | ALA4028917 | cell-free format | Scientific Literature | |
12. | ALA4033561 | ADME | Enzymatic stability of the compound in mouse plasma assessed observed rate constant | Mus musculus | 1 | ALA4028917 | cell-free format | Scientific Literature | |
13. | ALA4033562 | ADME | Enzymatic stability of the compound in human plasma assessed as half life | Homo sapiens | 1 | ALA4028917 | cell-free format | Scientific Literature | |
14. | ALA4033563 | ADME | Enzymatic stability of the compound in human plasma assessed observed rate constant | Homo sapiens | 1 | ALA4028917 | cell-free format | Scientific Literature | |
15. | ALA4033564 | Functional | Antinociceptive activity in CD1 mouse model of mechanical nociception assessed as increase in morphine-induced struggle response latency at 16 to 32 mg/kg, sc administered 30 mins before behavioral evaluation by paw pressure test | Mus musculus | 3 | ALA4028917 | organism-based format | Scientific Literature | |
16. | ALA4033571 | Binding | Binding affinity to dopamine D3 receptor in rat olfactory tubercle by liquid scintillation counting method | Rattus norvegicus | 1 | ALA4028917 | assay format | Scientific Literature | |
17. | ALA4033572 | Binding | Binding affinity to dopamine D4.2 receptor (unknown origin) by liquid scintillation counting method | Homo sapiens | 1 | ALA4028917 | assay format | Scientific Literature | |
18. | ALA4033573 | Binding | Binding affinity to 5-HT2A receptor in rat cortex by liquid scintillation counting method | Rattus norvegicus | 1 | ALA4028917 | assay format | Scientific Literature | |
19. | ALA4033574 | Binding | Binding affinity to 5-HT3 receptor in rat cortex by liquid scintillation counting method | Rattus norvegicus | 1 | ALA4028917 | assay format | Scientific Literature | |
20. | ALA4033575 | Binding | Binding affinity to adrenergic alpha1 receptor in rat cortex by liquid scintillation counting method | Rattus norvegicus | 1 | ALA4028917 | assay format | Scientific Literature |