#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4047126	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC2-associated AKT phosphorylation at S473 residue by Western blot analysis	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
2.	ALA4047133	Binding	Inhibition of DEPTOR in human RPMI8226 cells assessed as upregulation of mTORC1-dependant p21 expression at 0.5 to 2 uM after 6 hrs by Western blot analysis	Homo sapiens	4	ALA4043223	cell-based format	Scientific Literature
3.	ALA4047134	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.5 uM after 6 hrs by Western blot analysis relative to NSC126405	Homo sapiens	28	ALA4043223	cell-based format	Scientific Literature
4.	ALA4047135	Functional	Cytotoxicity against human RPMI8226 cells after 48 hrs by MTT assay	Homo sapiens	29	ALA4043223	cell-based format	Scientific Literature
5.	ALA4047136	Functional	Cytotoxicity against human MM1S cells after 48 hrs by MTT assay	Homo sapiens	29	ALA4043223	cell-based format	Scientific Literature
6.	ALA4047137	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated p70 phosphorylation at 0.25 uM after 6 hrs by Western blot analysis	Homo sapiens	5	ALA4043223	cell-based format	Scientific Literature
7.	ALA4047138	Functional	Induction of apoptosis in human RPMI8226 cells assessed as caspase3 activation at 0.12 to 2 uM after 48 hrs by cytofix/cytoperm staining based flow cytometry	Homo sapiens	6	ALA4043223	cell-based format	Scientific Literature
8.	ALA4047139	ADME	Cytotoxicity against PBL (unknown origin) after 48 hrs by MTT assay	Not specified	6	ALA4043223	cell-based format	Scientific Literature
9.	ALA4047140	Unassigned	Therapeutic index, ratio of IC50 for PBL (unknown origin) to IC50 for human RPMI8226 cells		6	ALA4043223	assay format	Scientific Literature
10.	ALA4047142	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells at 0.5 uM treated 6 hrs followed by DEPTOR immunoprecipitation by immunoblotting analysis	Homo sapiens	4	ALA4043223	cell-based format	Scientific Literature
11.	ALA4047143	Functional	Cytotoxicity against RAPTOR knockdown human RPMI8226 cells at 0.12 to 1 uM after 48 hrs by MTT assay	Homo sapiens	3	ALA4043223	cell-based format	Scientific Literature
12.	ALA4047144	Functional	Cytotoxicity against human RPMI8226 cells after 48 hrs in presence of mTOR inhibitor pp242 by MTT assay	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
13.	ALA4047145	Functional	Induction of apoptosis in human RPMI8226 cells assessed as caspase3 activation in presence of mTOR inhibitor pp242 by cytofix/cytoperm staining based flow cytometry	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
14.	ALA4047146	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated 4E-BP1 phosphorylation by Western blot analysis	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
15.	ALA4047147	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC1-associated S6 phosphorylation by Western blot analysis	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
16.	ALA4047148	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as increase in mTORC2-associated SGK phosphorylation by Western blot analysis	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
17.	ALA4047149	Binding	Inhibition of mTOR binding to DEPTOR in human RPMI8226 cells assessed as decrease in AKT phosphorylation at ser308 residue by Western blot analysis	Homo sapiens	2	ALA4043223	cell-based format	Scientific Literature
18.	ALA4047150	Toxicity	Toxicity in mouse xenografted with human RPMI8226 cells assessed as effect on RBC level at 20 mg/kg, ip administered daily for 3 days measured post last dose	Mus musculus	1	ALA4043223	organism-based format	Scientific Literature
19.	ALA4047151	Toxicity	Toxicity in mouse xenografted with human RPMI8226 cells assessed as effect on WBC level at 20 mg/kg, ip administered daily for 3 days measured post last dose	Mus musculus	1	ALA4043223	organism-based format	Scientific Literature
20.	ALA4047152	Toxicity	Toxicity in mouse xenografted with human RPMI8226 cells assessed as effect on platelet level at 20 mg/kg, ip administered daily for 3 days measured post last dose	Mus musculus	1	ALA4043223	organism-based format	Scientific Literature