# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3997239 | B | Agonist activity at rat alpha7 nAChR expressed in HEK293 cells assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Rattus norvegicus | 27 | ALA3994648 | cell-based format | Scientific Literature | |
2. | ALA3997240 | A | Antagonist activity at human 5HT3A receptor assessed as inhibition of 5-HT-induced calcium influx by Fluo-4-AM dye based FLIPR assay | Homo sapiens | 27 | ALA3994648 | single protein format | Scientific Literature | |
3. | ALA3997241 | U | Selectivity ratio of IC50 for antagonist activity at human 5HT3A receptor to EC50 for agonist activity at rat alpha7 nAChR expressed in HEK293 cells | 26 | ALA3994648 | cell-based format | Scientific Literature | ||
4. | ALA3997242 | B | Agonist activity at alpha4beta2 nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Homo sapiens | 27 | ALA3994648 | protein complex format | Scientific Literature | |
5. | ALA3997243 | B | Agonist activity at alpha3beta4 nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Homo sapiens | 27 | ALA3994648 | protein complex format | Scientific Literature | |
6. | ALA3997244 | B | Agonist activity at alpha1beta1deltaepsilon nAChR (unknown origin) assessed as increase in calcium influx measured for 2 mins by Fluo-4-AM dye based FLIPR assay | Homo sapiens | 27 | ALA3994648 | protein complex format | Scientific Literature |