# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4056590 | Binding | Inhibition of CYP51 in Trichophyton rubrum assessed as inhibition of microbe growth incubated for 48 hrs by CLSI M27-A3 guideline based method | Trichophyton rubrum | 3 | ALA4052712 | assay format | Scientific Literature | |
2. | ALA4056591 | Binding | Inhibition of CYP51 in Candida albicans assessed as inhibition of microbe growth incubated for 48 hrs by CLSI M27-A3 guideline based method | Candida albicans | 22 | ALA4052712 | assay format | Scientific Literature | |
3. | ALA4056592 | Binding | Inhibition of CYP51 in Aspergillus fumigatus assessed as inhibition of microbe growth incubated for 48 to 168 hrs by CLSI M27-A3 guideline based method | Aspergillus fumigatus | 22 | ALA4052712 | assay format | Scientific Literature | |
4. | ALA4056593 | ADME | Inhibition of CYP3A4 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS method | Homo sapiens | 22 | ALA4052712 | assay format | Scientific Literature | |
5. | ALA4056594 | Binding | Inhibition of CYP51 in Candida glabrata assessed as inhibition of microbe growth incubated for 48 hrs by CLSI M27-A3 guideline based method | Nakaseomyces glabratus | 3 | ALA4052712 | assay format | Scientific Literature | |
6. | ALA4056595 | Binding | Inhibition of CYP51 in Cryptococcus neoformans assessed as inhibition of microbe growth incubated for 48 hrs by CLSI M27-A3 guideline based method | Cryptococcus neoformans | 3 | ALA4052712 | assay format | Scientific Literature | |
7. | ALA4056596 | Binding | Inhibition of CYP51 in Aspergillus flavus assessed as inhibition of microbe growth incubated for 48 to 168 hrs by CLSI M27-A3 guideline based method | Aspergillus flavus | 3 | ALA4052712 | assay format | Scientific Literature | |
8. | ALA4056597 | ADME | Inhibition of CYP2C9 in human hepatocyte microsomes using diclofenac substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
9. | ALA4056598 | ADME | Inhibition of CYP2C19 in human hepatocyte microsomes using omeprazole substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
10. | ALA4056599 | ADME | Inhibition of CYP11B1 in human hepatocyte microsomes using deoxycortisol substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
11. | ALA4056600 | ADME | Inhibition of CYP11B2 in human hepatocyte microsomes using deoxycorticosteroid substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
12. | ALA4056601 | ADME | Inhibition of CYP17 lyase in human hepatocyte microsomes using 17a-hydroxypregnenolone substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
13. | ALA4056602 | ADME | Inhibition of CYP17 hydroxylase in human hepatocyte microsomes using pregnenolone substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
14. | ALA4056603 | ADME | Inhibition of CYP19 in human hepatocyte microsomes using testosterone substrate by HPLC/MS/MS method | Homo sapiens | 3 | ALA4052712 | assay format | Scientific Literature | |
15. | ALA4056604 | Binding | Binding affinity to Aspergillus fumigatus CYP51 | Aspergillus fumigatus | 1 | ALA4052712 | assay format | Scientific Literature | |
16. | ALA4056605 | ADME | Tmax in Swiss albino mouse at 5 mg/kg, po measured during 0.5 to 48 hrs post dose by HPLC/MS/MS method | Mus musculus | 1 | ALA4052712 | organism-based format | Scientific Literature | |
17. | ALA4056606 | ADME | Cmax in Swiss albino mouse at 5 mg/kg, po measured during 0.5 to 48 hrs post dose by HPLC/MS/MS method | Mus musculus | 1 | ALA4052712 | organism-based format | Scientific Literature | |
18. | ALA4056607 | ADME | AUClast in Swiss albino mouse at 5 mg/kg, po measured during 0.5 to 48 hrs post dose by HPLC/MS/MS method | Mus musculus | 1 | ALA4052712 | organism-based format | Scientific Literature | |
19. | ALA4056608 | ADME | Half life in Swiss albino mouse plasma at 5 mg/kg, po measured during 0.5 to 48 hrs post dose by HPLC/MS/MS method | Mus musculus | 1 | ALA4052712 | organism-based format | Scientific Literature | |
20. | ALA4056609 | ADME | Drug level in Swiss albino mouse kidney at 5 mg/kg, po after 48 hrs assessed as relative Cmax level relative to plasma drug level by HPLC/MS/MS method | Mus musculus | 1 | ALA4052712 | organism-based format | Scientific Literature |