| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4052313 | B | Binding affinity to captured wild-type human biotinylated Avi-tagged BCL6 BTB domain (5 to 129 amino acid residues) expressed in Escherichia coli BL21 (DE3) by SPR analysis | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 2. | ALA4052324 | B | Inhibition of VP16 activation domain-fused human BCOR (112 to 753 amino acid residues) binding to GAL4 DNA binding domain-fused wild-type human BCL6 (5 to 129 amino acid residues) expressed in HEK293T cell lysates after 20 hrs by firefly luciferase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4052325 | B | Inhibition of biotinylated C-terminal BCOR (unknown origin) binding to wild-type BCL6 BTB domain (5 to 129 amino acid residues) (unknown origin) by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 4. | ALA4380818 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of p53 mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA4380819 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of ATR mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 6. | ALA4380820 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of CXCR4 mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 7. | ALA4380821 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of CD69 mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 8. | ALA4380822 | B | Inhibition of BCL6 in human SUDHL4 cells assessed as de-repression of CDKN1A mRNA expression at 5 uM incubated for 24 hrs by RT-PCR analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4380846 | B | Binding affinity to recombinant human C-terminal GST-tagged BCL6 BTB domain C8Q/C67R/C84N triple mutant expressed in Escherichia coli BL21 (DE3) cells assessed as dissociation constant by biolayer interferometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4380849 | F | Antiproliferative activity against human SUDHL4 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA4380850 | F | Antiproliferative activity against human Farage cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4380851 | F | Antiproliferative activity against human DOHH2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA4380852 | F | Antiproliferative activity against human OCI-LY7 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 14. | ALA4380853 | F | Antiproliferative activity against BCL6-negative human Toledo cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4380854 | A | Cytotoxicity against human LO2 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4380855 | A | Cytotoxicity against HAF cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4380856 | A | Cytotoxicity against human NCM460 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4380857 | A | Cytotoxicity against human PNT1A cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4380890 | F | Antiproliferative activity against human SUDHL4 cells assessed as living cells and S phase cells at 0.625 uM incubated for 72 hrs by Edu based flow cytometry analysis (Rvb = 48.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4380891 | F | Antiproliferative activity against human SUDHL4 cells assessed as living cells and S phase cells at 1.25 uM incubated for 72 hrs by Edu based flow cytometry analysis (Rvb = 48.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature |
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