#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4040229	A	Drug metabolism assessed as recombinant human NEP-medited peptide proteolysis at 1 mM up to 72 hrs by LC-MS analysis	Homo sapiens	16		single protein format	Scientific Literature
2.	ALA4040230	A	Drug degradation in human plasma assessed as NEP-mediated degradation by measuring amount of apelin remaining after 30 mins by RP-HPLC analysis	Homo sapiens	16		single protein format	Scientific Literature
3.	ALA4040231	A	Drug degradation in human plasma assessed as NEP-mediated degradation by measuring amount of apelin remaining after 60 mins by RP-HPLC analysis	Homo sapiens	16		single protein format	Scientific Literature
4.	ALA4040233	B	Displacement of [125I]-pyr-1-apelin-13 from rat C-terminal EGFP-tagged APJ receptor expressed in CHO cell membranes after 3 hrs by Wallac gamma counting	Rattus norvegicus	16		cell-based format	Scientific Literature
5.	ALA4040234	F	Cardiovascular activity in anesthetized mouse assessed as increase in heart rate at 1.4 uM/kg, iv relative to control	Mus musculus	4		organism-based format	Scientific Literature
6.	ALA4040235	F	Cardiovascular activity in anesthetized mouse assessed as decrease in blood pressure at 1.4 uM/kg, iv relative to control	Mus musculus	8		organism-based format	Scientific Literature
7.	ALA5233304	A	Proteolytic stability assessed as recombinant human NEP-mediated compound degradation by measuring half life incubated for 24 hrs by LC-MS analysis	Homo sapiens	10		single protein format	Scientific Literature
8.	ALA5233306	A	Stability in human plasma assessed as half life at 1 mM measured for 24 hrs by LC-MS analysis	Homo sapiens	13		cell-free format	Scientific Literature
9.	ALA5233309	B	Displacement of [125I]-pyr-1-apelin-13 from EGFP tagged rat apelin receptor expressed in CHO cell membrane incubated for 3 hrs by gamma counter analysis	Rattus norvegicus	13		cell membrane format	Scientific Literature
10.	ALA5233310	B	Activation of recombinant human APJ receptor expressed in rat Chem-5 cells assessed as increase in Ca2+ mobilization by FLIPR Calcium 6-QF fluorescent dye based assay	Homo sapiens	13		cell-based format	Scientific Literature
11.	ALA5233311	F	Hypotensive effect in anesthetized wild type mouse assessed as change in mean arterial blood pressure at 1.4 uM/Kg, iv administered via right jugular vein measured for 60 mins	Mus musculus	13		organism-based format	Scientific Literature
12.	ALA5233312	F	Hypotensive effect in anesthetized wild type mouse assessed as total time duration of hypotensive effect at 1.4 uM/Kg, iv administered via right jugular vein measured for 60 mins	Mus musculus	13		organism-based format	Scientific Literature