| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4012294 | B | Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition after 30 mins in presence of [14C]-IPP by liquid scintillation counting analysis | Homo sapiens | 4 | ALA4011604 | single protein format | Scientific Literature | |
| 2. | ALA4012295 | B | Inhibition of recombinant FDPS (unknown origin) using GPP as substrate pretreated for 10 mins followed by substrate addition after 30 mins in presence of [14C]-IPP by liquid scintillation counting method | Homo sapiens | 3 | ALA4011604 | single protein format | Scientific Literature | |
| 3. | ALA4012297 | B | Inhibition of Rab GGTase2 in human RPMI8226 cells assessed as decrease in Rab GTPase geranylgeranylation by measuring accumulation of intracellular lambda light chain at 0.1 to 50 uM after 48 hrs by ELISA | Homo sapiens | 3 | ALA4011604 | cell-based format | Scientific Literature | |
| 4. | ALA4012298 | B | Inhibition of Rab GGTase2 in human RPMI8226 cells assessed as decrease in Rab6 geranylgeranylation at 5 to 50 uM after 48 hrs by western blot analysis | Homo sapiens | 2 | ALA4011604 | cell-based format | Scientific Literature | |
| 5. | ALA4012299 | B | Inhibition of recombinant rat GGTase1 expressed in Escherichia coli using GGDP as substrate measured after 2 hrs by dansyl-GCVLS dye based fluorescence assay | Rattus norvegicus | 3 | ALA4011604 | assay format | Scientific Literature | |
| 6. | ALA4012300 | B | Inhibition of recombinant rat FTase using FDP as substrate measured after 1 hr by dansyl-GCVLS dye based fluorescence assay | Rattus norvegicus | 3 | ALA4011604 | assay format | Scientific Literature | |
| 7. | ALA4012301 | B | Selectivity ratio of IC50 for recombinant GGDPS (unknown origin) to IC50 for recombinant FDPS (unknown origin) | Homo sapiens | 2 | ALA4011604 | assay format | Scientific Literature | |
| 8. | ALA4012302 | B | Inhibition of GGTase1 in human RPMI8226 cells assessed as decrease in Rap1a geranylgeranylation at 0.1 to 50 uM after 48 hrs by Western blot method | Homo sapiens | 2 | ALA4011604 | cell-based format | Scientific Literature |
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