| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4018047 | A | Inhibition of APMA-activated recombinant human MMP2 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay | Homo sapiens | 1 | ALA4017469 | cell-based format | Scientific Literature | |
| 2. | ALA4018050 | B | Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay | Homo sapiens | 44 | ALA4017469 | assay format | Scientific Literature | |
| 3. | ALA4018051 | A | Inhibition of recombinant human meprin alpha expressed in S2 insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assay | Homo sapiens | 2 | ALA4017469 | cell-based format | Scientific Literature | |
| 4. | ALA4018052 | A | Inhibition of APMA-activated recombinant human MMP9 expressed in CHO cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay | Homo sapiens | 1 | ALA4017469 | cell-based format | Scientific Literature | |
| 5. | ALA4018053 | A | Inhibition of APMA-activated recombinant human MMP13 expressed in mouse NS0 cells using Mca-PLGL-(DapDnp)-AR-NH2 as substrate by fluorescence assay | Homo sapiens | 1 | ALA4017469 | cell-based format | Scientific Literature | |
| 6. | ALA4018054 | A | Inhibition of recombinant human C-terminal His10-tagged ADAM10 expressed in baculovirus infected Sf21 cells using Abz-LANAVRSSSR-(DapDnp)-NH2 as substrate by fluorescence assay | Homo sapiens | 1 | ALA4017469 | cell-based format | Scientific Literature | |
| 7. | ALA4018055 | A | Inhibition of recombinant human C-terminal His6-tagged ADAM17 expressed in baculovirus infected Sf21 cells using Abz-LANAVRSSSR-(DapDnp)-NH2 as substrate by fluorescence assay | Homo sapiens | 1 | ALA4017469 | cell-based format | Scientific Literature | |
| 8. | ALA4018056 | U | Selectivity ratio of IC50 for recombinant human meprin alpha expressed in S2 insect cells to IC50 for recombinant human meprin beta expressed in yeast | Homo sapiens | 2 | ALA4017469 | cell-based format | Scientific Literature | |
| 9. | ALA4018062 | U | Selectivity ratio of IC50 for recombinant human C-terminal His10-tagged ADAM10 expressed in baculovirus infected Sf21 cells to IC50 for recombinant human meprin beta expressed in yeast | Homo sapiens | 2 | ALA4017469 | cell-based format | Scientific Literature | |
| 10. | ALA4189610 | A | Inhibition of human BMP1 expressed in Escherichia coli assessed as residual activity using Abz-YVADAPK(Dnp)G-OH as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | assay format | Scientific Literature | |
| 11. | ALA4189611 | B | Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assay | Homo sapiens | 44 | ALA4184323 | assay format | Scientific Literature | |
| 12. | ALA4189612 | A | Inhibition of recombinant human meprin alpha expressed in insect cells using Abz-YVADAPK(Dnp)G-OH as substrate by fluorescence assay | Homo sapiens | 6 | ALA4184323 | cell-based format | Scientific Literature | |
| 13. | ALA4189628 | A | Inhibition of human MMP2 assessed as residual activity using Mca-PLGL-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | single protein format | Scientific Literature | |
| 14. | ALA4189629 | A | Inhibition of human MMP9 assessed as residual activity using Mca-PLGL-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | single protein format | Scientific Literature | |
| 15. | ALA4189630 | A | Inhibition of human MMP13 assessed as residual activity using Mca-PLGL-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | single protein format | Scientific Literature | |
| 16. | ALA4189631 | A | Inhibition of human ADAM10 assessed as residual activity using Abz-LANAVRSSSR-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | single protein format | Scientific Literature | |
| 17. | ALA4189632 | A | Inhibition of human ADAM17 assessed as residual activity using Abz-LANAVRSSSR-(DapDnp)-AR-NH2 as substrate at 200 uM by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | single protein format | Scientific Literature | |
| 18. | ALA4189633 | A | Inhibition of recombinant human CYP3A4 expressed in baculosomes assessed as residual activity at 25 uM using BOMCC substrate by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | assay format | Scientific Literature | |
| 19. | ALA4189634 | A | Inhibition of recombinant human CYP2C9 expressed in baculosomes assessed as residual activity at 25 uM using BOMCC substrate by fluorescence assay relative to control | Homo sapiens | 6 | ALA4184323 | assay format | Scientific Literature | |
| 20. | ALA4189635 | F | Cytotoxicity in human SH-SY5Y cells assessed as cell viability at 30 uM after 24 hrs by CytoTox-ONE-based assay relative to control | Homo sapiens | 4 | ALA4184323 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!