| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4003671 | F | In vivo inhibition of chymotrypsin-like activity of 20S proteasome in blood cell of BALB/c mouse at 5 mg/kg, iv after 2 hrs using Suc-Leu-Leu-Val-Tyr-AMC substrate measured by fluorescence assay | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA4003672 | B | Inhibition of chymotrypsin-like activity of human 20S proteasome pretreated for 15 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by fluorescence assay | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 3. | ALA4003673 | F | Cytotoxicity against human RPMI8226 cells measured after 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 4. | ALA4003674 | F | Cytotoxicity against human MM1S cells measured after 72 hrs by MTS assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 5. | ALA4003675 | B | Inhibition of chymotrypsin-like activity of 20S proteasome in mouse blood at 2.5 uM pretreated for 40 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by fluorescence assay relative to control | Mus musculus | 7 | single protein format | Scientific Literature | ||
| 6. | ALA4003676 | A | Half-life in mouse plasma at 2 uM by LC-MS/MS analysis | Mus musculus | 2 | cell-free format | Scientific Literature | ||
| 7. | ALA4677868 | A | Half life in rat plasma at 2 uM by LC-MS/MS analysis | Rattus norvegicus | 8 | cell-free format | Scientific Literature |
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