| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4008737 | B | Inhibition of human FAAH1 expressed in HEK293 cell membrane-enriched lysate using AMC arachidonyl amide as substrate preincubated for 50 mins followed by substrate addition measured after 4 hrs by fluorescence analysis | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 2. | ALA4008738 | F | Agonist activity at recombinant human dopamine D3 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 3. | ALA4008739 | F | Agonist activity at recombinant human dopamine D3 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 30 mins by HTRF assay relative to dopamine | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 4. | ALA4008740 | F | Agonist activity at human dopamine D2 receptor-short expressed in CHO-K1 cells assessed as reduction in adenylyl cyclase activator NKH 477 induced cAMP accumulation preincubated for 10 mins followed by NKH 477 addition by HTRF assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 5. | ALA4008741 | F | Agonist activity at human dopamine D2 receptor-short expressed in CHO-K1 cells assessed as reduction in adenylyl cyclase activator NKH 477 induced cAMP accumulation preincubated for 10 mins followed by NKH 477 addition by HTRF assay relative to dopamine | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 6. | ALA4008742 | F | Agonist activity at recombinant human CB1 receptor expressed in CHO-K1 cells assessed as increase in cAMP accumulation after 20 mins by HTRF assay | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
| 7. | ALA4008745 | A | Half life in rat plasma at 2 uM by UPLC-MS analysis | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 8. | ALA4008746 | A | Cmax in Sprague-Dawley rat plasma at 3 mg/kg, iv by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4008747 | A | Half life in rat liver microsomes at 4.6 uM by UPLC-MS analysis | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 10. | ALA4008748 | A | Elimination half life in Sprague-Dawley rat plasma at 3 mg/kg, iv by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4008749 | A | Volume of distribution in Sprague-Dawley rat plasma at 3 mg/kg, iv by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4008750 | A | Clearance in Sprague-Dawley rat plasma at 3 mg/kg, iv by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4008751 | A | Cmax in Sprague-Dawley rat plasma at 10 mg/kg, po by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4008752 | A | Oral bioavailability in Sprague-Dawley rat brain at 10 mg/kg by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4008753 | A | Cmax in Sprague-Dawley rat brain at 10 mg/kg, po by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4008754 | A | AUC in Sprague-Dawley rat brain at 10 mg/kg, po by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4008755 | A | Total drug uptake in Sprague-Dawley rat brain at 10 mg/kg, po by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4008756 | A | Tmax in Sprague-Dawley rat plasma at 3 mg/kg, iv by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4008757 | A | Tmax in Sprague-Dawley rat brain at 10 mg/kg, po by UPLC-MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4008758 | B | Displacement of [3H](-)CGP12177 from human beta1 adrenergic receptor expressed in HEK293 cells at 10 to 100 nM after 45 mins by scintillation counting | Homo sapiens | 1 | cell-based format | Scientific Literature |
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