| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4016908 | B | Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 2. | ALA4016909 | A | Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 3. | ALA4016910 | U | Selectivity ratio of IC50 for human CYP11B2 expressed in hamster V79MZ cells to IC50 for human CYP11B1 expressed in hamster V79MZ cells | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
| 4. | ALA4016911 | B | Inhibition of rat CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]-11-deoxycorticosterone as substrate after 6 hrs by HPLC analysis | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA4016913 | A | Half life in human liver S9 fractions at 1 uM in presence of NADPH/UDPGA by LC-MS/MS analysis | Homo sapiens | 2 | tissue-based format | Scientific Literature | ||
| 6. | ALA4016914 | A | Half life in rat liver S9 fractions at 1 uM in presence of NADPH/UDPGA by LC-MS/MS analysis | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 7. | ALA4016915 | A | Inhibition of human CYP17A1 expressed in Escherichia coli membranes at 2 uM using [3H]-progesterone as substrate after 30 mins in presence of NADPH by HPLC analysis relative to control | Homo sapiens | 2 | cell membrane format | Scientific Literature | ||
| 8. | ALA4016916 | A | Inhibition of human placental microsomal CYP19A1 at 2 uM using [1beta-3H]-androstenedione as substrate after 20 mins in presence of NADPH by scintillation spectrometric method relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 9. | ALA4016917 | A | Inhibition of recombinant human CYP1A2 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 10. | ALA4016918 | A | Inhibition of recombinant human CYP2B6 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4016919 | A | Inhibition of recombinant human CYP2C9 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 12. | ALA4016920 | A | Inhibition of recombinant human CYP2C19 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 13. | ALA4016921 | A | Inhibition of recombinant human CYP2D6 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA4016922 | A | Inhibition of recombinant human CYP3A4 expressed in baculovirus infected insect cell microsomes at 1 uM relative to control | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4016923 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 66 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4016924 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 17. | ALA4016925 | T | Mutagenicity in Salmonella typhimurium TA98 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 18. | ALA4016926 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 19. | ALA4016927 | T | Mutagenicity in Salmonella typhimurium TA7001/7002/7003/7004/7005/7006 up to 100 uM in presence of rat liver S9 fraction by Ames 2 assay | Salmonella enterica subsp. enterica serovar Typhimurium | 2 | assay format | Scientific Literature | ||
| 20. | ALA4016928 | A | Agonist activity at AHR in human HepG2 cells assessed as activation of CYP1A1 at 3.16 uM preincubated for 48 hrs followed by CEC substrate addition measured after 30 mins by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature |
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