| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4009549 | Binding | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 1.9 +/- 0.15 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 2. | ALA4009550 | Binding | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells assessed as shift of half maximal vale for activation at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 3. | ALA4009551 | Binding | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 4. | ALA4009552 | Binding | Inhibition of recombinant rat Kv1.3 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 5. | ALA4009553 | ADME | Inhibition of recombinant rat Kv1.2 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 6. | ALA4009554 | ADME | Inhibition of recombinant rat Kv1.4 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 7. | ALA4009555 | ADME | Inhibition of recombinant rat Kv1.6 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 8. | ALA4009556 | ADME | Phototoxicity against HEK293 cells under UV irradiation | Homo sapiens | 3 | ALA4007435 | cell-based format | Scientific Literature | |
| 9. | ALA4009557 | Binding | Inhibition of recombinant rat Kv1.1 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 2 | ALA4007435 | cell-based format | Scientific Literature | |
| 10. | ALA4009558 | Binding | Inhibition of recombinant rat Kv(1.1)4 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 11. | ALA4009559 | Binding | Inhibition of recombinant rat Kv(1.1)3/Kv1.2 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 12. | ALA4009560 | Binding | Inhibition of recombinant rat Kv(1.1)2/Kv(1.2)2 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 13. | ALA4009561 | Binding | Inhibition of recombinant rat Kv1.1/Kv(1.2)3 expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 14. | ALA4009562 | ADME | Inhibition of recombinant rat Kv1.2(4) expressed in HEK293 cells at -90 mV holding potential by whole cell patch clamp Qpatch method | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 15. | ALA4009563 | Binding | Inhibition of recombinant rat Kv1.2/1.1/1.2/1.1 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 16. | ALA4009564 | Binding | Inhibition of recombinant rat Kv1.1/1.1/1.2/1.2 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 17. | ALA4009565 | Binding | Inhibition of recombinant rat Kv1.2/1.2/1.1/1.1 expressed in HEK293 cells at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method relative to control | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 18. | ALA4009566 | Binding | Inhibition of recombinant rat Kv1.1 concatamer expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 2.2 +/- 0.1 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 19. | ALA4009567 | Binding | Inhibition of recombinant rat Kv(1.1)2/Kv(1.2)2 expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 2.8 +/- 0.4 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature | |
| 20. | ALA4009568 | Binding | Inhibition of recombinant rat Kv(1.1)3/Kv1.2 expressed in HEK293 cells assessed as time constant for activation of Kv1.1 channel current at 10 uM at -90 mV holding potential by whole cell patch clamp Qpatch method (Rvb = 3.1 +/- 0.2 ms) | Rattus norvegicus | 1 | ALA4007435 | cell-based format | Scientific Literature |
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