# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4023557 | B | Inhibition of human BChE at 10 uM using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
2. | ALA4023563 | B | Inhibition of human erythrocyte AChE at 10 uM using ATC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Homo sapiens | 8 | single protein format | Scientific Literature | ||
3. | ALA4023567 | B | Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting method | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
4. | ALA4023569 | B | Inhibition of electric eel AChE at 100 uM using ATC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Electrophorus electricus | 6 | single protein format | Scientific Literature | ||
5. | ALA4023571 | B | Displacement of [3H]-CP55950 from human CB1 receptor expressed in CHO cell membranes at 10 uM after 3 hrs by scintillation counting method relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
6. | ALA4023573 | B | Inhibition of equine BChE using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method | Equus caballus | 4 | single protein format | Scientific Literature | ||
7. | ALA4023575 | A | Cytotoxicity against human U266 cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
8. | ALA4023576 | F | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in cAMP accumulation at 50 uM after 2 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
9. | ALA4023577 | F | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in AM630-induced cAMP accumulation at 50 uM after 2 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
10. | ALA4023578 | B | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in MIF mRNA expression at 50 uM after 2 hrs by qRT-PCR method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA4023579 | B | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in STAT3 mRNA expression at 50 uM after 2 hrs by qRT-PCR method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
12. | ALA4023580 | B | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in AM630-induced MIF mRNA expression at 50 uM after 2 hrs by qRT-PCR method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
13. | ALA4023581 | B | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in AM630-induced STAT3 mRNA expression at 50 uM after 2 hrs by qRT-PCR method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
14. | ALA4023582 | B | Displacement of [3H]-Diprenorphine from human mu opioid receptor expressed in HEK293-TSA cell membranes after 4 hrs by scintillation counting method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
15. | ALA4023583 | T | Toxicity in Swiss mouse assessed as body weight gain per day at 0.3 to 3 mg/kg, ip administered for 7 days measured during compound dosing | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA4023593 | F | Pro-cognitive activity in Swiss mouse assessed as decrease in amyloid beta (25 to 35)-induced alternation deficit at 1 to 3 mg/kg, ip administered for 7 days measured on day 8 by Y-maze test | Mus musculus | 2 | organism-based format | Scientific Literature | ||
17. | ALA4023595 | F | Pro-cognitive activity in Swiss mouse assessed as prevention of amyloid beta (25 to 35)-induced step through latency deficit at 3 mg/kg, ip administered for 7 days measured on day 10 by passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
18. | ALA4023597 | F | Pro-cognitive activity in Swiss mouse assessed as prevention of amyloid beta (25 to 35)-induced increase in escape latency at 1 to 3 mg/kg, ip administered for 7 days measured on day 10 by passive avoidance test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
19. | ALA4023598 | F | Pro-cognitive activity in amyloid beta (25 to 35)-treated Swiss mouse assessed as increase in locomotion by measuring number of arms entered during session at 3 mg/kg, ip administered for 7 days measured on day 8 by Y-maze test | Mus musculus | 2 | organism-based format | Scientific Literature | ||
20. | ALA5231902 | B | Inhibition of equine serum BChE | Equus caballus | 4 | single protein format | Scientific Literature |