# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4022867 | Binding | Displacement of [3H]-(+)-pentazocine from sigma 1 receptor in guinea pig brain membranes after 150 mins by liquid scintillation counting method | Cavia porcellus | 9 | ALA4020818 | cell membrane format | Scientific Literature | |
2. | ALA4022868 | Binding | Displacement of [3H]-DTG from sigma 2 receptor (unknown origin) after 120 mins by liquid scintillation counting method | Homo sapiens | 9 | ALA4020818 | single protein format | Scientific Literature | |
3. | ALA4022869 | Binding | Selectivity ratio of Ki for sigma 1 receptor in guinea pig brain membranes to Ki for sigma 2 receptor (unknown origin) | 9 | ALA4020818 | cell membrane format | Scientific Literature | ||
4. | ALA4022870 | Physicochemical | Solubility of the compound in water/methanol (1:1) mixture | 8 | ALA4020818 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA4022873 | Physicochemical | Stability of the compound in water/methanol (1:1) mixture assessed as nitric oxide release under light irradiation by amperometric detection method | 7 | ALA4020818 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA4022874 | Toxicity | Dark toxicity in human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4020818 | cell-based format | Scientific Literature | |
7. | ALA4022875 | Toxicity | Dark toxicity in human A2058 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4020818 | cell-based format | Scientific Literature | |
8. | ALA4022876 | Toxicity | Dark toxicity in human NCTC-2544 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4020818 | cell-based format | Scientific Literature | |
9. | ALA4022877 | Functional | Phototoxicity in human MCF7 cells assessed as decrease in cell viability at 10 to 50 uM preincubated for 24 hrs followed by light irradiation for 15 mins by MTT assay | Homo sapiens | 2 | ALA4020818 | cell-based format | Scientific Literature | |
10. | ALA4022878 | Toxicity | Dark toxicity in human MCF7 cells assessed as decrease in cell viability at 10 to 50 uM after 24 hrs by MTT assay | Homo sapiens | 1 | ALA4020818 | cell-based format | Scientific Literature | |
11. | ALA4022879 | Functional | Phototoxicity in human A2058 cells assessed as decrease in cell viability at 10 to 50 uM preincubated for 24 hrs followed by light irradiation for 15 mins by MTT assay | Homo sapiens | 1 | ALA4020818 | cell-based format | Scientific Literature | |
12. | ALA4022880 | Toxicity | Dark toxicity in human A2058 cells assessed as decrease in cell viability at 10 to 50 uM after 24 hrs by MTT assay | Homo sapiens | 1 | ALA4020818 | cell-based format | Scientific Literature | |
13. | ALA4022881 | ADME | Phototoxicity in human NCTC-2544 cells assessed as decrease in cell viability at 10 to 50 uM preincubated for 24 hrs followed by light irradiation for 15 mins by MTT assay | Homo sapiens | 2 | ALA4020818 | cell-based format | Scientific Literature | |
14. | ALA4022882 | Toxicity | Dark toxicity in human NCTC-2544 cells assessed as decrease in cell viability at 10 to 50 uM after 24 hrs by MTT assay | Homo sapiens | 2 | ALA4020818 | cell-based format | Scientific Literature | |
15. | ALA4022883 | ADME | Stability in human MCF7 cells assessed as nitric oxide release under light irradiation at 50 uM preincubated for 24 hrs followed by light irradiation for 15 mins by DCF-DA dye-based fluorescence microscopic method | Homo sapiens | 2 | ALA4020818 | cell-based format | Scientific Literature | |
16. | ALA4022884 | ADME | Stability in human MCF7 cells assessed as nitric oxide release under light irradiation at 50 uM preincubated for 24 hrs followed by light irradiation for 15 mins by Griess assay | Homo sapiens | 2 | ALA4020818 | cell-based format | Scientific Literature |