# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3992284 | B | Binding affinity to recombinant full-length N-terminal hexahistidine-tagged c-Myc (353 to 437 residues) bHLH-ZIP domain (unknown origin) expressed in Escherichia coli BL21 DE3 (pLysS) by fluorescence polarization assay | Homo sapiens | 27 | assay format | Patent Bioactivity Data | ||
2. | ALA3992296 | F | Cytotoxicity against human HL60 cells expressing c-Myc assessed as growth inhibition after 4 to 5 days by MTT assay | Homo sapiens | 16 | cell-based format | Patent Bioactivity Data | ||
3. | ALA3992297 | F | Cytotoxicity against human Daudi Burkitt lymphoma cells expressing c-Myc assessed as growth inhibition after 4 to 5 days by MTT assay | Homo sapiens | 15 | cell-based format | Patent Bioactivity Data | ||
4. | ALA3992300 | B | Inhibition of recombinant c-Myc/Max (unknown origin) expressed in human HL60 cells assessed as disruption of c-Myc/Max association after 6 hrs by co-immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
5. | ALA3992301 | B | Inhibition of recombinant c-Myc/Max (unknown origin) expressed in human HL60 cells assessed as disruption of c-Myc/Max association after 16 hrs by co-immunoprecipitation assay | Homo sapiens | 4 | cell-based format | Patent Bioactivity Data | ||
6. | ALA3992302 | U | Metabolic stability of the compound | 5 | assay format | Patent Bioactivity Data |