| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4022210 | F | Genotoxicity in human A2780 cells assessed as induction of DNA damage at 31 to 500 uM after 1 hr under pH 12.1 by comet assay | Homo sapiens | 4 | ALA4020779 | cell-based format | Scientific Literature | |
| 2. | ALA4022211 | F | Cytotoxicity against human A2780 cells after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 3. | ALA4022212 | F | Cytotoxicity against human HeLa cells after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 4. | ALA4022213 | F | Cytotoxicity against human LoVo cells after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 5. | ALA4022214 | F | Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 6. | ALA4022215 | F | Cytotoxicity against human M059J cells after 72 hrs by CCK8 assay | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 7. | ALA4022216 | F | Induction of DNA fragmentation in human A2780 cells assessed as viable cells at 0.083 uM after 24 hrs by BrdU/FITC staining-based TUNEL assay (Rvb = 96.1%) | Homo sapiens | 1 | ALA4020779 | cell-based format | Scientific Literature | |
| 8. | ALA4022217 | F | Genotoxicity in human A2780 cells assessed as induction of DNA damage after 1 hr under alkaline condition by comet assay | Homo sapiens | 4 | ALA4020779 | cell-based format | Scientific Literature | |
| 9. | ALA4022218 | F | Genotoxicity in human A2780 cells assessed as induction of DNA damage at 31 to 500 uM after 1 hr under neutral conditions by comet assay | Homo sapiens | 4 | ALA4020779 | cell-based format | Scientific Literature | |
| 10. | ALA4022219 | F | Genotoxicity in human A2780 cells assessed as induction of DNA damage at 125 uM after 1 hr under pH 12.1 by comet assay relative to control | Homo sapiens | 2 | ALA4020779 | cell-based format | Scientific Literature | |
| 11. | ALA4022220 | F | Genotoxicity in human A2780 cells assessed as induction of DNA damage at 500 uM after 1 hr under alkaline condition by comet assay relative to control | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 12. | ALA4022221 | F | Genotoxicity in human HeLa cells assessed as induction of DNA damage at 500 uM after 1 hr under alkaline condition by comet assay relative to control | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 13. | ALA4022222 | F | Genotoxicity in human LoVo cells assessed as induction of DNA damage at 500 uM after 1 hr under alkaline condition by comet assay relative to control | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 14. | ALA4022223 | F | Genotoxicity in human MCF7 cells assessed as induction of DNA damage at 500 uM after 1 hr under alkaline condition by comet assay relative to control | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 15. | ALA4022224 | F | Genotoxicity in human M059J cells assessed as induction of DNA damage at 500 uM after 1 hr under alkaline condition by comet assay relative to control | Homo sapiens | 7 | ALA4020779 | cell-based format | Scientific Literature | |
| 16. | ALA4022233 | F | Induction of DNA fragmentation in human A2780 cells at 50 uM incubated for 1 hr followed by compound wash out measured within 120 mins repair incubation period under alkaline condition by comet assay | Homo sapiens | 3 | ALA4020779 | cell-based format | Scientific Literature | |
| 17. | ALA4022235 | F | Induction of oxidative stress in human A2780 cells assessed as increase in ROS level in cytoplasm at IC20 after 1 hr by H2DCF-DA probe based fluorescence assay | Homo sapiens | 5 | ALA4020779 | cell-based format | Scientific Literature | |
| 18. | ALA4022236 | F | Induction of oxidative stress in human A2780 cells assessed as increase in ROS level in cytoplasm at IC50 after 1 hr by H2DCF-DA probe based fluorescence assay | Homo sapiens | 5 | ALA4020779 | cell-based format | Scientific Literature | |
| 19. | ALA4022243 | F | Induction of apoptosis in human A2780 cells assessed as viable cells at 0.083 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 93.9%) | Homo sapiens | 1 | ALA4020779 | cell-based format | Scientific Literature | |
| 20. | ALA4022244 | F | Induction of apoptosis in human A2780 cells assessed as apoptotic cells at 0.083 uM after 24 hrs by Annexin-V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 2%) | Homo sapiens | 1 | ALA4020779 | cell-based format | Scientific Literature |
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