# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4029972 | B | Inhibition of human CYP11B2-CLE9 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay | Homo sapiens | 31 | ALA4028827 | cell-based format | Scientific Literature | |
2. | ALA4029973 | A | Inhibition of human CYP11B1-8C7 expressed in Chinese hamster V79 cells using 11-deoxycortisol as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay | Homo sapiens | 31 | ALA4028827 | cell-based format | Scientific Literature | |
3. | ALA4029974 | U | Selectivity ratio of IC50 for human CYP11B1-8C7 expressed in Chinese hamster V79 cells to IC50 for human CYP11B2-CLE9 expressed in Chinese hamster V79 cells | Homo sapiens | 31 | ALA4028827 | cell-based format | Scientific Literature | |
4. | ALA4029975 | B | Inhibition of rat CYP11B2-1F4 expressed in Chinese hamster V79 cells using 11-deoxycorticosterone as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay | Rattus norvegicus | 5 | ALA4028827 | cell-based format | Scientific Literature | |
5. | ALA4029976 | B | Inhibition of human CYP17 expressed in African green monkey COS7 cells using 17-hydroxypregnenolone as substrate preincubated for 1 hr followed by substrate addition measured after 3 hrs by EIA | Homo sapiens | 5 | ALA4028827 | cell-based format | Scientific Literature | |
6. | ALA4029977 | B | Inhibition of CYP19 (unknown origin) using MFC as substrate and NADPH as cofactor preincubated for 10 mins with cofactor followed by substrate/enzyme addition measured after 30 mins | Homo sapiens | 5 | ALA4028827 | single protein format | Scientific Literature | |
7. | ALA4029978 | B | Inhibition of human CYP21 expressed in African green monkey COS7 cells using 17-hydroxypregnenolone as substrate preincubated for 1 hr followed by substrate addition measured for 3 hrs by HTRF assay | Homo sapiens | 5 | ALA4028827 | cell-based format | Scientific Literature | |
8. | ALA4029979 | A | Inhibition of hepatic CYP3A4 (unknown origin) | Homo sapiens | 5 | ALA4028827 | single protein format | Scientific Literature | |
9. | ALA4029980 | A | Inhibition of hepatic CYP2C9 (unknown origin) | Homo sapiens | 5 | ALA4028827 | single protein format | Scientific Literature | |
10. | ALA4029981 | A | Inhibition of hepatic CYP2D6 (unknown origin) | Homo sapiens | 5 | ALA4028827 | single protein format | Scientific Literature |