| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4021741 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by measuring remaining NO level at 20 ug/ml after 22 hrs by Griess assay relative to control | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 2. | ALA4021743 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production by measuring nitrate level at 20 ug/ml after 22 hrs by Griess assay (Rvb = 25.31 uM) | Mus musculus | 30 | cell-based format | Scientific Literature | ||
| 3. | ALA4021746 | F | Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO production after 22 hrs by Griess assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4021747 | A | Cytotoxicity against mouse RAW264.7 cells assessed as survival up to 20 ug/ml after 22 hrs by MTT assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4021748 | A | Cytotoxicity against mouse RAW264.7 cells assessed as survival at 40 ug/ml after 22 hrs by MTT assay relative to control | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4021749 | F | Downregulation of LPS-stimulated iNOS protein expression level in mouse RAW264.7 cells preincubated for 30 mins followed by LPS stimulation for 16 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4021750 | F | Downregulation of LPS-stimulated iNOS mRNA expression level in mouse RAW264.7 cells preincubated for 30 mins followed by LPS stimulation for 4 hrs by RT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4021751 | F | Downregulation of LPS-stimulated TNF-alpha protein expression level in mouse RAW264.7 cells up to 20 ug/ml preincubated for 30 mins followed by LPS stimulation for 4 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4021752 | F | Downregulation of LPS-stimulated IL-1beta protein expression level in mouse RAW264.7 cells up to 20 ug/ml preincubated for 30 mins followed by LPS stimulation for 4 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4021753 | F | Downregulation of LPS-stimulated IL-1beta mRNA expression level in mouse RAW264.7 cells preincubated for 30 mins followed by LPS stimulation for 4 hrs by RT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4021754 | B | Inhibition of NF-kB transcriptional activity in LPS-stimulated mouse RAW264.7 cells up to 20 ug/ml preincubated for 2 hrs followed by LPS stimulation for 16 hrs by SEAP reporter gene assay | Mus musculus | 1 | assay format | Scientific Literature | ||
| 12. | ALA4021755 | B | Inhibition of IkB kinase in LPS-stimulated mouse RAW264.7 cells assessed as reduction in IkB-alpha phosphorylation up to 20 ug/ml preincubated with cells followed by LPS stimulation for 30 mins by Western blot analysis | Mus musculus | 1 | assay format | Scientific Literature | ||
| 13. | ALA4021756 | F | Downregulation of IkB-alpha level in LPS-stimulated mouse RAW264.7 cells up to 20 ug/ml preincubated with cells followed by LPS stimulation for 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4021757 | F | Downregulation of IKKbeta level in LPS-stimulated mouse RAW264.7 cells up to 20 ug/ml preincubated with cells followed by LPS stimulation for 16 hrs by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4021758 | B | Inhibition of LPS-stimulated IRF-3 phosphorylation at Ser-396 residue in mouse RAW264.7 cells up to 20 ug/ml preincubated for 30 mins followed by LPS stimulation for 30 mins by Western blot analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4021759 | F | Downregulation of IFN-beta mRNA level in LPS-stimulated mouse RAW264.7 cells up to 20 ug/ml preincubated with cells followed by LPS stimulation for 4 hrs by RT-PCR method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4021760 | F | Upregulation of HO-1 protein level in LPS-stimulated mouse RAW264.7 cells at 20 ug/ml preincubated for 30 mins followed by LPS stimulation for 16 hrs by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature |
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