| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4024931 | B | Inhibition of full length recombinant human N-terminal His tagged BKT expressed in baculovirus infected Sf9 insect cells using poly (Glu,Tyr)4:1 as substrate pretreated for 60 mins followed by substrate addition after 1 hr by ADP-Glo luminescence assay | Homo sapiens | 49 | cell-based format | Scientific Literature | ||
| 2. | ALA4024935 | B | Irreversible inhibition of recombinant full length wild-type 3'-FLAG-tagged BTK (unknown origin) expressed in HEK293T cells assessed as reduction in Y223 phosphorylation measured after 4 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4024936 | B | Irreversible inhibition of recombinant full length 3'-FLAG-tagged BTK C481S mutant (unknown origin) expressed in HEK293T cells assessed as reduction in Y223 phosphorylation measured after 4 hrs by Western blot method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA4024940 | F | Growth inhibition of human SU-DHL-2 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 5. | ALA4024941 | F | Growth inhibition of human MV411 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 6. | ALA4024942 | F | Growth inhibition of human U2932 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 7. | ALA4024943 | F | Growth inhibition of human Ramos cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 8. | ALA4024944 | F | Growth inhibition of human OCI-AML3 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 9. | ALA4024945 | F | Growth inhibition of human Pfeiffer cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 10. | ALA4024946 | F | Growth inhibition of human U937 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA4024947 | F | Growth inhibition of human NB4 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA4024948 | F | Growth inhibition of human SKM1 cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4024949 | F | Growth inhibition of human M07e cells | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4024965 | F | Cell cycle arrest in human Pfeiffer cells assessed as increase in accumulation at G0/G1 phase at 10 uM after 48 hrs by propidium iodide/RNase staining based flow cytometric method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA4024966 | F | Cell cycle arrest in human U2932 cells assessed as increase in accumulation at G0/G1 phase at 10 uM after 48 hrs by propidium iodide/RNase staining based flow cytometric method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA4024967 | F | Induction of apoptosis in human U2932 cells assessed as induction of PARP cleavage at 10 uM after 48 hrs by immunoblot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA4024968 | F | Induction of apoptosis in human Pfeiffer cells assessed as induction of PARP cleavage at 10 uM after 48 hrs by immunoblot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA4025452 | F | Induction of apoptosis in human U2932 cells assessed as induction of caspase-3 cleavage at 10 uM after 48 hrs by immunoblot | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA4025453 | F | Induction of apoptosis in human Pfeiffer cells assessed as induction of caspase-3 cleavage at 10 uM after 48 hrs by immunoblot | Homo sapiens | 3 | cell-based format | Scientific Literature |
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