# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4020851 | Binding | Inhibition of chymotrypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Suc-Leu-Leu-Val-Tyr-AMC substrate addition by fluorescence assay | Homo sapiens | 13 | ALA4020701 | cell-based format | Scientific Literature | |
2. | ALA4020852 | Binding | Inhibition of caspase-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Z-Leu-Leu-Glu-AMC substrate addition by fluorescence assay | Homo sapiens | 13 | ALA4020701 | cell-based format | Scientific Literature | |
3. | ALA4020853 | Binding | Inhibition of trypsin-like activity of 20S proteasome in human red blood cells pretreated for 20 mins followed by Boc-Leu-Arg-Arg-AMC substrate addition by fluorescence assay | Homo sapiens | 13 | ALA4020701 | cell-based format | Scientific Literature | |
4. | ALA4020854 | Binding | Inhibition of human FAS thioster domain preincubated for 30 mins followed by 4-methylumbelliferyl heptanoate substrate addition measured every 5 mins for 60 mins by fluorescence assay | Homo sapiens | 13 | ALA4020701 | single protein format | Scientific Literature | |
5. | ALA4020855 | Functional | Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay | Homo sapiens | 13 | ALA4020701 | cell-based format | Scientific Literature |