# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4052063 | Toxicity | Genotoxicity in Salmonella typhimurium TAT1535 in presence of rat liver S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 9 | ALA4049449 | assay format | Scientific Literature | |
2. | ALA4052064 | Toxicity | Genotoxicity in Salmonella typhimurium TA97 in presence of rat liver S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 9 | ALA4049449 | assay format | Scientific Literature | |
3. | ALA4052065 | Toxicity | Genotoxicity in Salmonella typhimurium TA98 in presence of rat liver S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 9 | ALA4049449 | assay format | Scientific Literature | |
4. | ALA4052066 | Toxicity | Genotoxicity in Salmonella typhimurium TA100 in presence of rat liver S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 9 | ALA4049449 | assay format | Scientific Literature | |
5. | ALA4052067 | Toxicity | Genotoxicity in Salmonella typhimurium TA102 in presence of rat liver S9 fraction by Ames test | Salmonella enterica subsp. enterica serovar Typhimurium | 9 | ALA4049449 | assay format | Scientific Literature | |
6. | ALA4052068 | Unassigned | Glutathione reactivity assessed as GSH adduct formation | 1 | ALA4049449 | assay format | Scientific Literature | ||
7. | ALA4052069 | Binding | Inhibition of human ERG channel | Homo sapiens | 1 | ALA4049449 | single protein format | Scientific Literature | |
8. | ALA4052070 | ADME | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA4049449 | single protein format | Scientific Literature | |
9. | ALA4052071 | ADME | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA4049449 | single protein format | Scientific Literature | |
10. | ALA4052072 | ADME | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4049449 | single protein format | Scientific Literature | |
11. | ALA4052073 | Physicochemical | Solubility of the compound in phosphate buffer solution at pH 6.5 by HPLC-UV analysis | 1 | ALA4049449 | small-molecule physicochemical format | Scientific Literature | ||
12. | ALA4052074 | Physicochemical | Permeability of the compound by PAMPA | 1 | ALA4049449 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA4052075 | Physicochemical | Octanol-phosphate buffer partition co-efficient, log D of the compound at pH 7.4 after 24 hrs by shake flask method | 1 | ALA4049449 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA4052096 | Binding | Modulation of patient derived full length SMN2 pre mRNA splicing assessed as inclusion of exon 7 | Homo sapiens | 37 | ALA4049449 | assay format | Scientific Literature | |
15. | ALA4052097 | Binding | Modulation of patient derived full length SMN2 pre mRNA splicing assessed as restoration of functional SMN2 to protein level | Homo sapiens | 38 | ALA4049449 | assay format | Scientific Literature | |
16. | ALA4052103 | ADME | Drug metabolism in human plasma assessed as amide bond hydrolysis at 1 uM after 15 to 300 mins by LC-MS/MS analysis | Homo sapiens | 1 | ALA4049449 | cell-free format | Scientific Literature | |
17. | ALA4052104 | ADME | Drug metabolism in mouse plasma assessed as amide bond hydrolysis at 1 uM after 15 to 300 mins by LC-MS/MS analysis | Mus musculus | 1 | ALA4049449 | cell-free format | Scientific Literature | |
18. | ALA4052105 | ADME | Drug metabolism in rat plasma assessed as amide bond hydrolysis at 1 uM after 15 to 300 mins by LC-MS/MS analysis | Rattus norvegicus | 1 | ALA4049449 | cell-free format | Scientific Literature | |
19. | ALA4052106 | Physicochemical | Stability at various pH levels assessed as amide bond hydrolysis | 1 | ALA4049449 | small-molecule physicochemical format | Scientific Literature |