# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4059398 | B | Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by fluorescence based assay | Homo sapiens | 22 | assay format | Scientific Literature | ||
2. | ALA4059399 | B | Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by fluorescence based assay | Homo sapiens | 22 | assay format | Scientific Literature | ||
3. | ALA4059400 | B | Inhibition of human N-terminal MBP-fused NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by fluorescence based assay | Homo sapiens | 22 | assay format | Scientific Literature | ||
4. | ALA4059401 | B | Inhibition of human CathA-IRES-6His-tagged NEU1 expressed in HEK293T cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition measured after 30 mins by fluorescence based assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
5. | ALA4418863 | B | Inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 71 | cell-based format | Patent Bioactivity Data | ||
6. | ALA4418864 | B | Inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
7. | ALA4418865 | B | Inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
8. | ALA4418866 | B | Inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli pre-incubated for 15 mins before 4MU-NANA substrate addition and measured after 30 mins by fluorescence based assay | Homo sapiens | 67 | assay format | Patent Bioactivity Data | ||
9. | ALA4418868 | B | Selectivity index, ratio of IC50 for inhibition of His6-tagged human neuraminidase-1 expressed in HEK293 cells to IC50 for inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli | Homo sapiens | 20 | cell-based format | Patent Bioactivity Data | ||
10. | ALA4418870 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal GST tagged human neuraminidase-4 expressed in Escherichia coli to IC50 for inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli | Homo sapiens | 6 | assay format | Patent Bioactivity Data | ||
11. | ALA4418871 | B | Selectivity index, ratio of IC50 for inhibition of N-terminal MBP tagged human neuraminidase-2 expressed in Escherichia coli to IC50 for inhibition of N-terminal MBP tagged human neuraminidase-3 expressed in Escherichia coli | Homo sapiens | 19 | assay format | Patent Bioactivity Data |