# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4017397 | Binding | Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using varying levels of fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by Lineweaver-Burk plot analysis | Homo sapiens | 7 | ALA4014357 | cell-based format | Scientific Literature | |
2. | ALA4017398 | Binding | Inhibition of full length recombinant human MMP13 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 14 | ALA4014357 | cell-based format | Scientific Literature | |
3. | ALA4017399 | Binding | Inhibition of recombinant human MMP1 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | ALA4014357 | cell-based format | Scientific Literature | |
4. | ALA4017400 | Binding | Inhibition of recombinant human MMP2 expressed in mouse NSO cells using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | ALA4014357 | cell-based format | Scientific Literature | |
5. | ALA4017401 | Binding | Inhibition of MMP8 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | ALA4014357 | single protein format | Scientific Literature | |
6. | ALA4017402 | Binding | Inhibition of MMP9 (unknown origin) using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | ALA4014357 | single protein format | Scientific Literature | |
7. | ALA4017403 | Binding | Inhibition of recombinant human MMP14 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition measured immediately by fluorescence assay | Homo sapiens | 9 | ALA4014357 | single protein format | Scientific Literature | |
8. | ALA4017411 | Binding | Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen at 20 uM after 24 hrs by SDS-PAGE analysis relative to control | Homo sapiens | 9 | ALA4014357 | single protein format | Scientific Literature | |
9. | ALA4017412 | Binding | Inhibition of MMP13 (unknown origin)-mediated type-2 collagen cleavage assessed as increase in intact collagen after 24 hrs by SDS-PAGE analysis | Homo sapiens | 3 | ALA4014357 | single protein format | Scientific Literature | |
10. | ALA4017413 | Binding | Inhibition of ACE (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
11. | ALA4017414 | Binding | Inhibition of ACE2 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
12. | ALA4017415 | Binding | Inhibition of ADAM10 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
13. | ALA4017416 | Binding | Inhibition of BACE1 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
14. | ALA4017417 | Binding | Inhibition of caspase1 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
15. | ALA4017418 | Binding | Inhibition of caspase2 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
16. | ALA4017419 | Binding | Inhibition of caspase3 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
17. | ALA4017420 | Binding | Inhibition of caspase5 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
18. | ALA4017421 | Binding | Inhibition of caspase6 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
19. | ALA4017422 | Binding | Inhibition of caspase7 (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature | |
20. | ALA4017423 | Binding | Inhibition of cathepsin-D (unknown origin) at 1 uM relative to control | Homo sapiens | 2 | ALA4014357 | single protein format | Scientific Literature |